Analysis of signs and pathology of H5N1-infected ducks from the 2010–2011 Korean highly pathogenic avian influenza outbreak suggests the influence of age and management practices on severity of disease
| العنوان: | Analysis of signs and pathology of H5N1-infected ducks from the 2010–2011 Korean highly pathogenic avian influenza outbreak suggests the influence of age and management practices on severity of disease |
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| المؤلفون: | You-Chan Bae, Soon-Seek Yoon, Woo-Hee Park, Moon-Young Rhyoo, Ji-Youl Jung, Kyung-Hyun Lee, Kyu-Shik Jeong, Mi-Ran Ki, Myoung-Heon Lee, Eun-Joo Lee, Oun-Kyung Moon, Hye-Ryoung Kim |
| المصدر: | Avian Pathology. 44:175-181 |
| بيانات النشر: | Informa UK Limited, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Pathology, medicine.medical_specialty, animal structures, viruses, animal diseases, Disease, Biology, medicine.disease_cause, Virus, Disease Outbreaks, Food Animals, Republic of Korea, Influenza A virus, medicine, Animals, Viral shedding, Antigens, Viral, Poultry Diseases, Influenza A Virus, H5N1 Subtype, General Immunology and Microbiology, Myocardium, Mortality rate, Histological Techniques, Age Factors, Brain, virus diseases, food and beverages, Outbreak, Immunohistochemistry, Virology, Influenza A virus subtype H5N1, Ducks, Influenza in Birds, Animal Science and Zoology, Viral load |
| الوصف: | We compared the clinical signs, histopathological lesions and distribution of viral antigens among infected young (meat-type) and older (breeder) ducks that were naturally infected with the highly pathogenic avian influenza (HPAI) virus during the 2010-2011 Korean outbreak. The meat-type ducks had a high mortality rate (30%) and showed severe neurological signs such as head tremors and paresis. In contrast, HPAI-infected breeder ducks had minimal clinical signs but a decreased egg production rate. The histopathological characteristics of infected meat-type ducks included necrotic lesions of heart and brain, which may have primarily contributed to the high mortality rate. In contrast, the breeder ducks only presented necrotic splenitis, and viral antigens were only detected in the trachea, lungs and spleen. Younger ducks had a high viral titre in the organs, high levels of viral shedding and a high mortality rate after experimental HPAI virus infection. Compared to the breeder ducks, the meat-type ducks were raised in smaller farms that had poor quarantine and breeding facilities. It is therefore possible that better biosecurity in the breeder farms could have reduced the infection dose and subsequently the severity of the disease. Thus, age and management may be the influencing factors for HPAI susceptibility in ducks. |
| تدمد: | 1465-3338 0307-9457 2010-2011 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::accf885a950ca74182f4b32837551ec2 https://doi.org/10.1080/03079457.2015.1021295 |
| رقم الأكسشن: | edsair.doi.dedup.....accf885a950ca74182f4b32837551ec2 |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 14653338 03079457 20102011 |
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