Early Visual Symptom Patterns in Inherited Retinal Dystrophies

التفاصيل البيبلوغرافية
العنوان: Early Visual Symptom Patterns in Inherited Retinal Dystrophies
المؤلفون: Eric Troeger, Elena Prokofyeva, Eberhart Zrenner, Robert Wilke
المصدر: Ophthalmologica. 226:151-156
بيانات النشر: S. Karger AG, 2011.
سنة النشر: 2011
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Visual acuity, Adolescent, genetic structures, Photophobia, Vision Disorders, Visual Acuity, Young Adult, Night vision, Ophthalmology, parasitic diseases, Retinitis pigmentosa, medicine, Humans, Age of Onset, Child, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Infant, Retrospective cohort study, General Medicine, Middle Aged, medicine.disease, eye diseases, Sensory Systems, Visual field, Child, Preschool, Female, Visual Fields, Age of onset, medicine.symptom, business, Retinitis Pigmentosa, Retinal Dystrophies
الوصف: The present retrospective study compared initial visual symptom patterns in inherited retinal dystrophies (IRD) on the basis of records of 544 patients diagnosed with a wide variety of IRD at the Tuebingen University Eye Hospital from 2005 to 2008. Age at first onset of symptoms was noted, and the following clinical data were analyzed: visual acuity (VA), night vision disturbances, photophobia, onset of visual field defects, best corrected VA, and types of visual field defects. Median age at visual symptom onset was defined with 25th and 75th percentiles and compared in 15 IRD types. The main trends in VA changes in retinitis pigmentosa and cone-rod dystrophies were identified. This study was the first to combine disease history and clinical data analysis in such a wide variety of IRD. It showed that patterns of initial symptoms in IRD can provide extra clues for early differential diagnosis and inclusion of IRD patients in clinical trials.
تدمد: 1423-0267
0030-3755
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad809945b5d4657e1246afde5ce6d3b7
https://doi.org/10.1159/000330381
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....ad809945b5d4657e1246afde5ce6d3b7
قاعدة البيانات: OpenAIRE