Determination of Individual Ultrafiltration Time (Apex) and Purification Phosphate Time by Peritoneal Equilibration Test: Application to Individual Peritoneal Dialysis Modality Prescription in Children
| العنوان: | Determination of Individual Ultrafiltration Time (Apex) and Purification Phosphate Time by Peritoneal Equilibration Test: Application to Individual Peritoneal Dialysis Modality Prescription in Children |
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| المؤلفون: | J. Geisert, Didier Eyer, Philippe Desprez, Michel Fischbach, Ahmed Lahlou |
| المصدر: | Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis. 16:557-561 |
| بيانات النشر: | SAGE Publications, 1996. |
| سنة النشر: | 1996 |
| مصطلحات موضوعية: | Male, Time Factors, Adolescent, medicine.medical_treatment, 030232 urology & nephrology, Ultrafiltration, Peritoneal equilibration test, Phosphates, Peritoneal dialysis, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Reference Values, Dialysis Solutions, medicine, Homeostasis, Humans, 030212 general & internal medicine, Child, P phosphate, Chromatography, Chemistry, Continuous ambulatory peritoneal dialysis, Infant, General Medicine, Water-Electrolyte Balance, Phosphate, Apex (geometry), Dwell time, Nephrology, Child, Preschool, Kidney Failure, Chronic, Female, Peritoneum, Peritoneal Dialysis |
| الوصف: | Efficiency of peritoneal dialysis (PD) is dependent on adequate ultrafiltration (UF) and purification (solute clearance). These two goals apparently seem to conflict in terms of duration of dwells: short dwell time enhances UF capacity and, conversely, long dwell time enhances solute clearance. Peritoneal equilibration test (PET) allows an approach to the ultrafiltration time: the point at which the over time dialysate urea saturation and glucose desaturation curves cross, called APEX time. PET also allows an approach to the purification time: the point at which dialysate-to-plasma (DIP) concentration ratios over time are high. Because of the value of phosphate as a uremic factor of morbidity, we have chosen the time at which DIP phosphate is equal to 0.6 as a purification phosphate dwell time (PPT). A total of 17 patients were studied, over a five-year period, allowing 142 determinations. APEX times (range 18 71 min) and PPT (range 105 -238 min) were spread over a wide distribution. PPT and APEX times were significantly shorter in children younger than three years of age than in children older than ten years of age. PPT were nearly four times longer than APEX times. Knowledge of these conflicting ultrafiltration and purification times should help, in our view, in the individual choice of the PD modality: if UF is the major goal, short dwell times should be used (automated PD); if purification is the major goal, long dwell times should be used, as in continuous ambulatory peritoneal dialysis; if both are the target goal, tidal PD should be discussed. |
| تدمد: | 1718-4304 0896-8608 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add8e500db39e37ebb2586a01575b8c7 https://doi.org/10.1177/089686089601601s115 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....add8e500db39e37ebb2586a01575b8c7 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17184304 08968608 |
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