Spectrum of Hemoglobinopathies Among the Primitive Tribes
| العنوان: | Spectrum of Hemoglobinopathies Among the Primitive Tribes |
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| المؤلفون: | Mahrukh Wadia, Kumar S. Ashokan, Yazdi M. Italia, Rajni Kaul, Dipika Mohanty, Vasantha Muthuswamy, Kanjaksha Ghosh, Dipty Jain, Malay B. Mukherjee, Roshan B. Colah, Guru Prasad Chottray, Deepak Kumar Shukla |
| المصدر: | Asia Pacific Journal of Public Health. 27:NP562-NP571 |
| بيانات النشر: | SAGE Publications, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Hemoglobin s, Health plan, Traditional medicine, business.industry, Anemia, Hemoglobin, Sickle, Public Health, Environmental and Occupational Health, Ethnic group, India, medicine.disease, Hemoglobinopathies, Hemoglobinopathy, Gene Frequency, Population Groups, Humans, Medicine, Statistical analysis, business, Allele frequency, Chromatography, High Pressure Liquid, Regional differences, Demography |
| الوصف: | We evaluated the spectrum of hemoglobinopathies among the primitive tribal groups from 4 states in India. A total of 15 200 individuals from 14 primitive tribal groups were studied by automated high-performance liquid chromatography. The hemoglobin S (HbS) allele frequency varied from 0.011 to 0.120 and the β-thalassemia allele frequency from 0.005 to 0.024. It is interesting to note that a very high HbS allele frequency was observed among the Dravidian (0.060-0.120) and Indo-European (0.060-0.076) as compared with Austro-Asiatic (0.011-0.022) speaking tribal groups. Although statistical analysis of the data did not show any ethnic differences within the states, regional differences were observed between the states for both HbS and β-thalassemia traits. HbS was found to be the most common hemoglobinopathy followed by β-thalassemia. A health plan for identifying sickle-cell homozygotes in the neonatal period with proper medical intervention is desirable. |
| تدمد: | 1941-2479 1010-5395 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0522daa3c25d349ae0258030a123ab9 https://doi.org/10.1177/1010539513480231 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....b0522daa3c25d349ae0258030a123ab9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19412479 10105395 |
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