SYSTEMIC ENCEPHALITOZOONOSIS DUE TOENCEPHALITOZOON CUNICULISTRAIN IV IN A VANCOUVER ISLAND MARMOT (MARMOTA VANCOUVERENSIS)
| العنوان: | SYSTEMIC ENCEPHALITOZOONOSIS DUE TOENCEPHALITOZOON CUNICULISTRAIN IV IN A VANCOUVER ISLAND MARMOT (MARMOTA VANCOUVERENSIS) |
|---|---|
| المؤلفون: | Pauline Delnatte, Nicole M. Nemeth, Hugh Y. Cai, Ellie L. Milnes |
| المصدر: | Journal of Zoo and Wildlife Medicine. 49:484-488 |
| بيانات النشر: | American Association of Zoo Veterinarians, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, 0301 basic medicine, Pathology, medicine.medical_specialty, Obtundation, 040301 veterinary sciences, Interstitial nephritis, 030106 microbiology, H&E stain, Biology, Microsporidiosis, Rodent Diseases, 0403 veterinary science, 03 medical and health sciences, Fatal Outcome, medicine, Animals, Internal transcribed spacer, Encephalitozoon cuniculi, British Columbia, General Veterinary, Endangered Species, 04 agricultural and veterinary sciences, General Medicine, medicine.disease, biology.organism_classification, Encephalitozoonosis, Marmota, Animals, Zoo, Animal Science and Zoology, Vasculitis |
| الوصف: | A 2-mo-old Vancouver Island marmot ( Marmota vancouverensis), housed at a quarantined breeding facility, presented for acute obtundation and vestibular ataxia. Physical examination revealed poor growth compared with littermates, poor nutritional condition, and mild dehydration. The animal's condition deteriorated over 24 hr, and it was euthanized following the development of generalized seizures. No gross abnormalities were observed upon postmortem evaluation. Histologic evaluation revealed severe, multifocal, granulomatous and lymphoplasmacytic meningoencephalomyelitis and interstitial nephritis, with intralesional, intracytoplasmic spore-filled, parasitophorous vacuoles and segmental, multi-organ, fibrinoid vasculitis (disseminated encephalitozoonosis). The etiologic agent was evident by hematoxylin and eosin and Gram-chromotrope stains, and confirmed as Encephalitozoon cuniculi by polymerase chain reaction on brain tissue. Sequencing of the internal transcribed spacer region of the rRNA gene showed 100% homology with E. cuniculi strain IV, which is a newly described genotype. This is the first report of encephalitozoonosis in this critically endangered species. |
| تدمد: | 1937-2825 1042-7260 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15e945d01a69ab786b2e897bc522109 https://doi.org/10.1638/2017-0175.1 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....b15e945d01a69ab786b2e897bc522109 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19372825 10427260 |
|---|