A comparison of depth of necrosis among adjuvant therapies used for the treatment of benign bone tumors
| العنوان: | A comparison of depth of necrosis among adjuvant therapies used for the treatment of benign bone tumors |
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| المؤلفون: | Brenden Bombardier, Kyle R. Sweeney, Douglas R. Haase, Tanner Poppe, Elizabeth Friedman, Nicole Hughes |
| المصدر: | Journal of Surgical Oncology. 123:1299-1303 |
| بيانات النشر: | Wiley, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Necrosis, medicine.medical_treatment, Bone Neoplasms, 03 medical and health sciences, 0302 clinical medicine, medicine, Adjuvant therapy, Humans, business.industry, Chemoradiotherapy, Adjuvant, General Medicine, Prognosis, medicine.disease, Argon beam, Curettage, Oncology, 030220 oncology & carcinogenesis, 030211 gastroenterology & hepatology, Surgery, medicine.symptom, business, Nuclear medicine, Benign bone tumors, Adjuvant, Giant-cell tumor of bone, Cellular necrosis |
| الوصف: | BACKGROUND AND OBJECTIVES Benign bone tumors are often treated with extended curettage utilizing an adjuvant therapy to eliminate any remaining tumor cells. The purpose of this study was to explore and compare the histologic depth of necrosis created by various adjuvant therapies used in the treatment of benign bone tumors. METHODS A high-speed burr was utilized to create cortical defects within porcine humeri and femora. Phenol, polymethyl methacrylate (PMMA), argon beam coagulation (ABC), liquid nitrogen, and the Bipolar Hemostatic Sealer (BHS) were each applied to five defects, with an additional five defects left untreated as a control. The maximal depth of necrosis was determined under microscopic examination. RESULTS The phenol, PMMA, ABC, liquid nitrogen, and BHS demonstrated an average histologic depth of necrosis of 0.30, 0.78, 2.54, 2.54, and 0.92 mm, respectively, each of which was significantly increased compared to the control group (p = .001, .003, .003, .01, and |
| تدمد: | 1096-9098 0022-4790 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2673f8ce63f82c5130ac610306913cf https://doi.org/10.1002/jso.26397 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....b2673f8ce63f82c5130ac610306913cf |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10969098 00224790 |
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