Evaluation of left ventricular ejection fraction using through-time radial GRAPPA

التفاصيل البيبلوغرافية
العنوان: Evaluation of left ventricular ejection fraction using through-time radial GRAPPA
المؤلفون: Vikas Gulani, Victoria Yeh, Abdus Sattar, Gunhild Aandal, Robert C. Gilkeson, Nicole Seiberlich, Trevor Jenkins, Mark A. Griswold, Vidya Nadig, Prabhakar Rajiah
المصدر: Journal of Cardiovascular Magnetic Resonance
بيانات النشر: Springer Science and Business Media LLC, 2014.
سنة النشر: 2014
مصطلحات موضوعية: Left ventricular ejection fraction, medicine.medical_specialty, Time Factors, Real-time imaging, Cardiac-Gated Imaging Techniques, Blood volume, 030204 cardiovascular system & hematology, Ventricular Function, Left, 030218 nuclear medicine & medical imaging, Breath Holding, Electrocardiography, 03 medical and health sciences, 0302 clinical medicine, Heart Rate, Predictive Value of Tests, Internal medicine, Image Interpretation, Computer-Assisted, medicine, Humans, Radiology, Nuclear Medicine and imaging, Prospective Studies, End-systolic volume, Ohio, Medicine(all), Observer Variation, Ejection fraction, Radiological and Ultrasound Technology, medicine.diagnostic_test, business.industry, Research, Cardiac function, Reproducibility of Results, Stroke Volume, Magnetic resonance imaging, Stroke volume, Magnetic Resonance Imaging, medicine.anatomical_structure, Ventricle, Linear Models, Cardiology, End-diastolic volume, Cardiovascular magnetic resonance, Artifacts, Cardiology and Cardiovascular Medicine, business, Nuclear medicine
الوصف: Background The determination of left ventricular ejection fraction using cardiovascular magnetic resonance (CMR) requires a steady cardiac rhythm for electrocardiogram (ECG) gating and multiple breathholds to minimize respiratory motion artifacts, which often leads to scan times of several minutes. The need for gating and breathholding can be eliminated by employing real-time CMR methods such as through-time radial GRAPPA. The aim of this study is to compare left ventricular cardiac functional parameters obtained using current gold-standard breathhold ECG-gated functional scans with non-gated free-breathing real-time imaging using radial GRAPPA, and to determine whether scan time or the occurrence of artifacts are reduced when using this real-time approach. Methods 63 patients were scanned on a 1.5T CMR scanner using both the standard cardiac functional examination with gating and breathholding and the real-time method. Total scan durations were noted. Through-time radial GRAPPA was employed to reconstruct images from the highly accelerated real-time data. The blood volume in the left ventricle was assessed to determine the end systolic volume (ESV), end diastolic volume (EDV), and ejection fraction (EF) for both methods, and images were rated for the presence of artifacts and quality of specific image features by two cardiac readers. Linear regression analysis, Bland-Altman plots and two-sided t-tests were performed to compare the quantitative parameters. A two-sample t-test was performed to compare the scan durations, and a two-sample test of proportion was used to analyze the presence of artifacts. For the reviewers´ ratings the Wilcoxon test for the equality of the scores’ distributions was employed. Results The differences in EF, EDV, and ESV between the gold-standard and real-time methods were not statistically significant (p-values of 0.77, 0.82, and 0.97, respectively). Additionally, the scan time was significantly shorter for the real-time data collection (p
تدمد: 1532-429X
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42764115c008b4c5de0a27eca7e98ba
https://doi.org/10.1186/s12968-014-0079-8
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....b42764115c008b4c5de0a27eca7e98ba
قاعدة البيانات: OpenAIRE