Preservation of genetic variation in a breeding population for long-term genetic gain
| العنوان: | Preservation of genetic variation in a breeding population for long-term genetic gain |
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| المؤلفون: | Steven Maenhout, Bernard De Baets, Jan Fostier, David Vanavermaete |
| المصدر: | G3-GENES GENOMES GENETICS G3: Genes, Genomes, Genetics, Vol 10, Iss 8, Pp 2753-2762 (2020) G3: Genes|Genomes|Genetics |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 0106 biological sciences, qtl fixation, genetic gain, Animal breeding, GENOMEWIDE SELECTION, PREDICTION, Quantitative Trait Loci, Population, Biology, Quantitative trait locus, QH426-470, 01 natural sciences, shared data resoureces, 03 medical and health sciences, Genetic variation, shared data resources, Medicine and Health Sciences, Genetics, plant breeding, Animals, genpred, Genetics(clinical), GENOMIC SELECTION, Selection, Genetic, education, Molecular Biology, Genetics (clinical), genomic prediction, 030304 developmental biology, 0303 health sciences, education.field_of_study, Truncation selection, Models, Genetic, VALUES, QTL fixation, Genetic Variation, Biology and Life Sciences, QUANTITATIVE TRAITS, simulation study, Fixation (population genetics), Genetic gain, Evolutionary biology, RELIABILITY, 010606 plant biology & botany, Premature convergence |
| الوصف: | Genomic selection has been successfully implemented in plant and animal breeding. The transition of parental selection based on phenotypic characteristics to genomic selection (GS) has reduced breeding time and cost while accelerating the rate of genetic progression. Although breeding methods have been adapted to include genomic selection, parental selection often involves truncation selection, selecting the individuals with the highest genomic estimated breeding values (GEBVs) in the hope that favorable properties will be passed to their offspring. This ensures genetic progression and delivers offspring with high genetic values. However, several favorable quantitative trait loci (QTL) alleles risk being eliminated from the breeding population during breeding. We show that this could reduce the mean genetic value that the breeding population could reach in the long term with up to 40%. In this paper, by means of a simulation study, we propose a new method for parental mating that is able to preserve the genetic variation in the breeding population, preventing premature convergence of the genetic values to a local optimum, thus maximizing the genetic values in the long term. We do not only prevent the fixation of several unfavorable QTL alleles, but also demonstrate that the genetic values can be increased by up to 15 percentage points compared with truncation selection. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2160-1836 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42953a5ae78e903ac173cd40bc98b3f https://biblio.ugent.be/publication/8665657/file/8665658 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....b42953a5ae78e903ac173cd40bc98b3f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 21601836 |
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