التفاصيل البيبلوغرافية
العنوان:
RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo
المؤلفون:
Jessica Sebastiani , Michela Puxeddu , Marianna Nalli , Ruoli Bai , Ludovica Altieri , Paola Rovella , Eugenio Gaudio , Daniela Trisciuoglio , Filippo Spriano , Patrizia Lavia , Cinzia Fionda , Domiziana Masci , Andrea Urbani , Chiara Bigogno , Giulio Dondio , Ernest Hamel , Francesco Bertoni , Romano Silvestri , Giuseppe La Regina
بيانات النشر:
Elsevier France-Editions Scientifiques Medicales Elsevier, 2023.
سنة النشر:
2023
مصطلحات موضوعية:
Pharmacology , Synthesis , Lymphoma , Mitotic arrest , Pyrrole , Tubulin , Organic Chemistry , Drug Discovery , General Medicine
الوصف:
We synthesized a new inhibitor of tubulin polymerization, the pyrrole (1-(7H-pyrrolo[2,3- d]pyrimidin-4-yl)-1H-pyrrol-3-yl)(3,4,5-trimethoxy-phenyl)methanone 6 (RS6077). Compound 6 inhibited the growth of multiple cancer cell lines, with IC
اللغة:
English
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b627b1f33ba1c80296963a7e5f365b5c https://hdl.handle.net/11573/1669754
حقوق:
CLOSED
رقم الأكسشن:
edsair.doi.dedup.....b627b1f33ba1c80296963a7e5f365b5c
قاعدة البيانات:
OpenAIRE
