Diagnosis of Nontuberculous Mycobacteria Lung Disease
| العنوان: | Diagnosis of Nontuberculous Mycobacteria Lung Disease |
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| المؤلفون: | Michael R. Loebinger, Steven Cowman |
| المصدر: | Seminars in Respiratory and Critical Care Medicine. 39:343-350 |
| بيانات النشر: | Georg Thieme Verlag KG, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Lung Diseases, Pulmonary and Respiratory Medicine, Pathology, medicine.medical_specialty, Isolation (health care), Mycobacterium Infections, Nontuberculous, Disease, Critical Care and Intensive Care Medicine, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, medicine, Humans, Clinical significance, 030212 general & internal medicine, biology, medicine.diagnostic_test, business.industry, Respiratory disease, Sputum, Nontuberculous Mycobacteria, bacterial infections and mycoses, medicine.disease, biology.organism_classification, Review article, Bronchoalveolar lavage, 030228 respiratory system, Nontuberculous mycobacteria, medicine.symptom, Tomography, X-Ray Computed, business, Bronchoalveolar Lavage Fluid |
| الوصف: | The diagnosis of pulmonary nontuberculous mycobacteria (NTM) disease may be challenging, as their presence alone does not necessarily indicate disease and diagnosis requires the integration of clinical, radiological, and microbiological findings. The first step is to suspect NTM disease; however, clinical manifestations of NTM are nonspecific and it may not be possible to separate them from those caused by underlying respiratory disease. The radiological appearance generally falls into two patterns, fibrocavitary disease and nodular-bronchiectatic disease; consolidation, infiltrates, and solitary nodules are also described. The isolation of NTM from clinical samples is fundamental to the diagnosis and they may be cultured from sputum, bronchoalveolar lavage fluid, or tissue specimens. If sputum is used, more than one isolate is required for diagnosis due to the propensity of NTM to contaminate clinical samples. The correct identification of NTM is vital, as their clinical relevance varies widely between species, and treatment is dictated by the identity of the isolated organism. This review covers the clinical presentation of NTM disease, the interpretation of radiological findings, and issues surrounding the isolation and identification of mycobacteria. |
| تدمد: | 1098-9048 1069-3424 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b738e01fca0a070ab92b0ebba1b07cbc https://doi.org/10.1055/s-0038-1651493 |
| رقم الأكسشن: | edsair.doi.dedup.....b738e01fca0a070ab92b0ebba1b07cbc |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10989048 10693424 |
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