Hard surface biocontrol in hospitals using microbial-based cleaning products
| العنوان: | Hard surface biocontrol in hospitals using microbial-based cleaning products |
|---|---|
| المؤلفون: | Robin Temmerman, Elisabetta Caselli, Sante Mazzacane, Alessio Branchini, Alessia Frabetti, Daniela Platano, Alberta Vandini, Paola Antonioli, P. G. Balboni |
| المصدر: | PLoS ONE PLoS ONE, Vol 9, Iss 9, p e108598 (2014) |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Hospital setting, Microorganism, Colony Count, Microbial, Biological pest control, lcsh:Medicine, Biology, Research and Analysis Methods, Microbiology, NO, Antibiotic resistance, healthcare associated infections, Medicine and Health Sciences, microbial cleaning products, Public and Occupational Health, Sanitation, lcsh:Science, Cross Infection, Multidisciplinary, Bacillus pumilus, business.industry, Probiotics, lcsh:R, Biology and Life Sciences, Food grade, Biocontrol, Hygiene, Contamination, biology.organism_classification, Hospitals, Biotechnology, Health Care, Disinfection, Infectious Diseases, Healthcare-Associated Infections, lcsh:Q, Biocontrol, healthcare associated infections, microbial cleaning products, Pathogen load, business, Environmental Health, Research Article, Equipment Preparation |
| الوصف: | Background Healthcare-Associated Infections (HAIs) are one of the most frequent complications occurring in healthcare facilities. Contaminated environmental surfaces provide an important potential source for transmission of many healthcare-associated pathogens, thus indicating the need for new and sustainable strategies. Aim This study aims to evaluate the effect of a novel cleaning procedure based on the mechanism of biocontrol, on the presence and survival of several microorganisms responsible for HAIs (i.e. coliforms, Staphyloccus aureus, Clostridium difficile, and Candida albicans) on hard surfaces in a hospital setting. Methods The effect of microbial cleaning, containing spores of food grade Bacillus subtilis, Bacillus pumilus and Bacillus megaterium, in comparison with conventional cleaning protocols, was evaluated for 24 weeks in three independent hospitals (one in Belgium and two in Italy) and approximately 20000 microbial surface samples were collected. Results Microbial cleaning, as part of the daily cleaning protocol, resulted in a reduction of HAI-related pathogens by 50 to 89%. This effect was achieved after 3–4 weeks and the reduction in the pathogen load was stable over time. Moreover, by using microbial or conventional cleaning alternatively, we found that this effect was directly related to the new procedure, as indicated by the raise in CFU/m2 when microbial cleaning was replaced by the conventional procedure. Although many questions remain regarding the actual mechanisms involved, this study demonstrates that microbial cleaning is a more effective and sustainable alternative to chemical cleaning and non-specific disinfection in healthcare facilities. Conclusions This study indicates microbial cleaning as an effective strategy in continuously lowering the number of HAI-related microorganisms on surfaces. The first indications on the actual level of HAIs in the trial hospitals monitored on a continuous basis are very promising, and may pave the way for a novel and cost-effective strategy to counteract or (bio)control healthcare-associated pathogens. |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e4ed105b83d5b7d87331cc4a781989 https://hdl.handle.net/11392/2050612 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....b7e4ed105b83d5b7d87331cc4a781989 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |