High lncSNHG15 expression may predict poor cancer prognosis: a meta-analysis based on the PRISMA and the bio-informatics analysis
| العنوان: | High lncSNHG15 expression may predict poor cancer prognosis: a meta-analysis based on the PRISMA and the bio-informatics analysis |
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| المؤلفون: | Xi xian Ke, Cheng Chen, Gang Xu, Hong Ling Lu, Shi xu Fang, Qiang Guo |
| المصدر: | Bioscience Reports |
| بيانات النشر: | Portland Press Ltd., 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Oncology, medicine.medical_specialty, Biophysics, Cochrane Library, Biochemistry, Disease-Free Survival, Neoplasms, Internal medicine, Biomarkers, Tumor, medicine, Humans, Stage (cooking), Molecular Biology, Diagnostics & Biomarkers, Research Articles, Cancer, Neoplasm Staging, SNHG15, business.industry, Pharmacology & Toxicology, Hazard ratio, Computational Biology, Cell Biology, Publication bias, Prognosis, medicine.disease, LncRNA, Confidence interval, Tumor Burden, meta-analysis, Gene Expression Regulation, Neoplastic, Lymphatic Metastasis, Meta-analysis, Cell Cycle, Growth & Proliferation, Biomarker (medicine), RNA, Long Noncoding, Neoplasm Grading, business |
| الوصف: | Background: SNHG15 has been reported to be aberrantly expressed in various tumor tissues and could serve as a promising prognostic cancer biomarker. Previous studies on SNHG15 yielded inconsistent results with insufficient sampling. Here, a meta-analysis was conducted to investigate the prognostic value of SNHG15 in multiple cancers. Methods: Relevant studies were retrieved from six electronic databases including PubMed, Cochrane Library, Google Scholar, Embase, Web of Science and China National Knowledge Infrastructure (CNKI). Fifteen publications comprising 1318 patients were included. The publication bias was identified by the Begg’s Test, and the sensitivity analysis was also performed. Results: The results demonstrated a positive correlation between high expression level of lncSNHG15 and short overall survival (hazard ratio (HR) = 2.07, 95% confidence interval (CI), 1.48–2.88; P |
| تدمد: | 1573-4935 0144-8463 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b053eafea40f161934a670e2644df4 https://doi.org/10.1042/bsr20194468 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....b8b053eafea40f161934a670e2644df4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15734935 01448463 |
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