The effect of punctal plugs in reducing ocular surface irritation after povidone-iodine preparation of intravitreal injection—a randomized trial
| العنوان: | The effect of punctal plugs in reducing ocular surface irritation after povidone-iodine preparation of intravitreal injection—a randomized trial |
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| المؤلفون: | Kamran M. Riaz, Haoxing D. Jin, Kai Ding, Henry R Marsh, Stanley S K Park, John W Surbeck, Ronald M Kingsley, Vinay A Shah |
| المصدر: | Eye (Lond) |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Punctal plug, medicine.medical_specialty, genetic structures, Ocular irritation, chemistry.chemical_element, Eye, Iodine, medicine.disease_cause, Article, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, Ophthalmology, medicine, Humans, Povidone-Iodine, business.industry, Dry eyes, medicine.disease, eye diseases, chemistry, Eye dryness, Tears, Intravitreal Injections, Punctal Plugs, 030221 ophthalmology & optometry, Dry Eye Syndromes, sense organs, Irritation, business, Ocular surface, 030217 neurology & neurosurgery |
| الوصف: | PURPOSE: To evaluate the utility of dissolvable collagen punctal plugs (CPP) in reducing ocular surface irritation after intravitreal injections (IVI). METHODS: Sixty-four subjects in the experimental group received CPP after intravitreal injections. Sixty-two controls did not receive CPP. Reductions in the Ocular Surface Disease Index(©) (OSDI) and Standardized Patient Evaluation of Eye Dryness II (SPEED II) scores were analysed. RESULTS: Dry eye symptoms, as measured by reductions from the pre- to post-injection OSDI (p = 0.137) and SPEED II (p = 0.381) scores, did not significantly differ between the two groups. In sub-group analysis, patients with objective findings of dry eyes had significant improvement in their symptoms (p = 0.046) with CPP. The effect of CPP is not significant in those without dry eyes (p = 0.27). CONCLUSION: CPPs were not effective in reducing post-injection ocular irritation in patients with no or only mild dry eye symptoms. CPPs improved patients’ post-injection comfort levels in those who had moderate-to-severe symptoms and objective findings of dry eye. Though costly CPP could be considered in selective patients. A standardized eye rinse could be a simple, efficacious, and cost-effective way to reduce post-injection ocular irritation; however, more studies are needed. |
| تدمد: | 1476-5454 0950-222X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8da2b1489da306a47cee0f03f4cee41 https://doi.org/10.1038/s41433-021-01476-3 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....b8da2b1489da306a47cee0f03f4cee41 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14765454 0950222X |
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