Evaluation of myocardial viability in myocardial infarction patients by magnetic resonance perfusion and delayed enhancement imaging
| العنوان: | Evaluation of myocardial viability in myocardial infarction patients by magnetic resonance perfusion and delayed enhancement imaging |
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| المؤلفون: | Lin Sun, Xin-Xiang Zhao, F Yang, Renhui Cai, W Yuan, W Sun |
| المصدر: | Herz. 44:735-742 |
| بيانات النشر: | Springer Science and Business Media LLC, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, Cardiac function curve, medicine.medical_specialty, Magnetic Resonance Spectroscopy, Heart Ventricles, medicine.medical_treatment, Myocardial Infarction, Contrast Media, Infarction, Delayed enhancement, 030204 cardiovascular system & hematology, Revascularization, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Humans, 030212 general & internal medicine, Myocardial infarction, medicine.diagnostic_test, business.industry, Myocardium, Heart, Magnetic resonance imaging, medicine.disease, Magnetic Resonance Imaging, medicine.anatomical_structure, Ventricle, Cardiology, Cardiology and Cardiovascular Medicine, business, Perfusion |
| الوصف: | Cardiovascular magnetic resonance imaging (CMR) has been established as a modality to detect myocardial viability. The aim of this study was to evaluate myocardial viability by observing transmural extent of infraction and microvascular perfusion level.We performed CMR in 30 myocardial infarction (MI) patients within 7-10 days. At the 6‑month follow-up, CMR was used to evaluate the impact of abnormal reperfusion and observe the transmural extent of infraction on recovery of function.The left ventricle was divided into 16 segments using the American Heart Association classification. Infarcts were detected in 202 of the 480 segments (42%) by delayed enhancement magnetic resonance imaging (DE-MRI). According to first-pass myocardial perfusion, abnormal perfusion was detected in 278 of 480 segments (60%), reduced perfusion was identified in 173 of 278 (62%), and perfusion defects in 105 of 278 segments (38%). The results showed that the segments with abnormal perfusion were larger than in DE-MRI (P 0.05), indicating that the area of abnormal perfusion segments extend significantly beyond the region of infarction. Microvascular perfusion with an infarcted region was lower compared to non-infarcted segments (P 0.05). The extent of myocardial hyperenhancement correlated inversely with microvascular perfusion (P 0.05). Segments with severe microvascular perfusion and75% transmural infarction on the 7‑ to 10-day scan had markedly increased at the 6‑month follow-up (P 0.01), indicating a lack of recovery of cardiac function.DE-MRI combined with microvascular perfusion may be effective to detect viable myocardium in patients with MI and may provide a means of predicting whether revascularization will be effective. |
| تدمد: | 1615-6692 0340-9937 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d25ad0e1175bad25e34d5c5c9aa119 https://doi.org/10.1007/s00059-018-4741-z |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....b9d25ad0e1175bad25e34d5c5c9aa119 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 16156692 03409937 |
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