Amplifying Free Radical Generation of AIE Photosensitizer with Small Singlet–Triplet Splitting for Hypoxia-Overcoming Photodynamic Therapy
| العنوان: | Amplifying Free Radical Generation of AIE Photosensitizer with Small Singlet–Triplet Splitting for Hypoxia-Overcoming Photodynamic Therapy |
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| المؤلفون: | Ya-Fang Xiao, Wen-Cheng Chen, Jia-Xiong Chen, Guihong Lu, Shuang Tian, Xiao Cui, Zhen Zhang, Huan Chen, Yingpeng Wan, Shengliang Li, Chun-Sing Lee |
| المصدر: | ACS Applied Materials & Interfaces. 14:5112-5121 |
| بيانات النشر: | American Chemical Society (ACS), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Drug Carriers, Mice, Inbred BALB C, Photosensitizing Agents, Light, Phosphatidylethanolamines, Imidazoles, Mice, Nude, Polyethylene Glycols, Mice, Photochemotherapy, A549 Cells, Neoplasms, NIH 3T3 Cells, Animals, Humans, Nanoparticles, Tumor Hypoxia, Female, General Materials Science, Reactive Oxygen Species, Phenanthrolines |
| الوصف: | Type-I photodynamic therapy (PDT) with less oxygen consumption shows great potential for overcoming the vicious hypoxia typically observed in solid tumors. However, the development of type-I PDT is hindered by insufficient radical generation and the ambiguous design strategy of type-I photosensitizers (PSs). Therefore, developing highly efficient type-I PSs and unveiling their structure-function relationship are still urgent and challenging. Herein, we develop two phenanthro[9,10 |
| تدمد: | 1944-8252 1944-8244 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4d06ddabe97c09fbb98ecab121de88 https://doi.org/10.1021/acsami.1c23797 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....ba4d06ddabe97c09fbb98ecab121de88 |
| قاعدة البيانات: | OpenAIRE |
Find this issue from the American Chemical Society | تدمد: | 19448252 19448244 |
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