Time requirements and health effects of participation in colorectal cancer screening with colonoscopy or computed tomography colonography in a randomized controlled trial
| العنوان: | Time requirements and health effects of participation in colorectal cancer screening with colonoscopy or computed tomography colonography in a randomized controlled trial |
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| المؤلفون: | Paul Fockens, M. C. de Haan, E. Dekker, T. R. de Wijkerslooth, Ewout W. Steyerberg, L. van Dam, Patrick M.M. Bossuyt, Jaap Stoker, M. van Ballegooijen, E. J. Kuipers, Maarten Thomeer, M E van Leerdam, Esther M. Stoop |
| المساهمون: | Graduate School, Other departments, Amsterdam Public Health, Epidemiology and Data Science, 10 Public Health & Methodologie, Amsterdam Gastroenterology Endocrinology Metabolism, Cancer Center Amsterdam, Gastroenterology and Hepatology, Radiology and Nuclear Medicine, Gastroenterology & Hepatology, Public Health, Radiology & Nuclear Medicine |
| المصدر: | Endoscopy, 45(3), 182-188. Georg Thieme Verlag |
| بيانات النشر: | Georg Thieme Verlag, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Time Factors, Colorectal cancer, Colonoscopy, Anxiety, Statistics, Nonparametric, law.invention, Quality of life, Randomized controlled trial, SDG 3 - Good Health and Well-being, Computed Tomography Colonography, Interquartile range, law, Internal medicine, Cancer screening, medicine, Humans, Prospective cohort study, neoplasms, Early Detection of Cancer, Aged, medicine.diagnostic_test, business.industry, Gastroenterology, Middle Aged, medicine.disease, digestive system diseases, Surgery, Patient Satisfaction, Quality of Life, Female, Self Report, business, Colorectal Neoplasms, Colonography, Computed Tomographic |
| الوصف: | Time limitations and unwanted health effects may act as barriers to participation in colorectal cancer (CRC) screening. The aim of the study was to measure the time requirements and health effects of colonoscopy and computed tomography colonography (CTC) screening. This was a prospective diary study in a consecutive sample within a randomized controlled CRC screening trial, comparing primary colonoscopy and CTC screening for average-risk individuals aged 50 - 74 years. The diary ended when all screening-related complaints had passed. The diary was returned by 75 % (241/322) of colonoscopy and 75 % (127/170) of CTC screenees. The median interval between leaving home and returning from the examination was longer for colonoscopy (4 hours and 18 minutes [4:18], interquartile range [IQR] 3:30 - 5:00) than for CTC (2:30 hours, IQR 2:06 - 3:00; P < 0.001). Similarly, the time to return to routine activities was longer after colonoscopy (3:54 hours, IQR 1:48 - 15:00) than after CTC (1:36 hours, IQR 0:54 - 4:42). The duration of screening-related symptoms after the examination was shorter for colonoscopy (11:00 hours, IQR 2:54 - 20:00) than for CTC (22:00 hours; IQR 5:30 - 47:00; P < 0.001). Abdominal complaints were reported more frequently after CTC. Anxiety, pain, and quality of life worsened during the screening process, with no differences between the two examinations. Compared with colonoscopy, CTC screening required less time and allowed screenees to return to their daily activities more quickly. In contrast, CTC was associated with a twofold longer duration of screening-related symptoms. Feelings of anxiety, pain, and quality of life scores were similar during colonoscopy and CTC screening. These results should be incorporated into cost-effectiveness analyses of CRC screening techniques |
| تدمد: | 1438-8812 0013-726X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5aebd3b384cb83d1b1c9dd45aabf3a https://pure.eur.nl/en/publications/4ca21789-b307-42dd-b7a9-2575b3ada857 |
| حقوق: | RESTRICTED |
| رقم الأكسشن: | edsair.doi.dedup.....ba5aebd3b384cb83d1b1c9dd45aabf3a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14388812 0013726X |
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