The Impact of Personality Pathology on Treatment Outcome in Late-life Panic Disorder
| العنوان: | The Impact of Personality Pathology on Treatment Outcome in Late-life Panic Disorder |
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| المؤلفون: | Richard C. Oude Voshaar, Bernice Gulpers, Sebastiaan P J van Alphen, M. Kampman, Frans R.J. Verhey, Gert-Jan Hendriks |
| المساهمون: | RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, Psychiatrie & Neuropsychologie, MUMC+: MA Med Staf Spec Psychiatrie (9), Clinical Cognitive Neuropsychiatry Research Program (CCNP), Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE) |
| المصدر: | Journal of Psychiatric Practice, 26, 3, pp. 164-174 Journal of Psychiatric Practice, 26, 164-174 Journal of Psychiatric Practice, 26(3), 164-174. LIPPINCOTT WILLIAMS & WILKINS |
| بيانات النشر: | LIPPINCOTT WILLIAMS & WILKINS, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Adult, Male, YOUNGER, Panic Disorder with Agoraphobia, Adolescent, medicine.medical_treatment, media_common.quotation_subject, ANXIETY DISORDERS, Stress-related disorders Donders Center for Medical Neuroscience [Radboudumc 13], behavioral disciplines and activities, elderly, Experimental Psychopathology and Treatment, Young Adult, mental disorders, medicine, Personality, Humans, personality disorders, OLDER-PEOPLE, panic disorder, COGNITIVE-BEHAVIORAL THERAPY, PREDICTORS, media_common, Aged, Cognitive Behavioral Therapy, business.industry, Panic disorder, Other Research Radboud Institute for Health Sciences [Radboudumc 0], Personality pathology, AGORAPHOBIA, Middle Aged, medicine.disease, EFFICACY, Personality disorders, PREVALENCE, Cognitive behavioral therapy, Paroxetine, treatment outcome, Female, business, COMORBIDITY, Anxiety disorder, Agoraphobia, Clinical psychology |
| الوصف: | Contains fulltext : 219370.pdf (Publisher’s version ) (Closed access) Background: Comorbid personality disorders are assumed to negatively interfere with the treatment outcome of affective disorders. Data on late-life panic disorder remain unknown. We examined the association of personality pathology and treatment outcome related to age and treatment modality. Methods: An observational study on the effectiveness of cognitive-behavioral therapy (CBT) for panic disorder with agoraphobia among patients 18 to 74 years of age and randomized controlled comparison of paroxetine and CBT in older patients (60 y of age or older) were performed. The diagnosis of panic disorder was confirmed by the Anxiety Disorder Interview Schedule-Revised (ADIS-IV) and personality features were assessed with the Personality Diagnostic Questionnaire. The impact of personality features on either agoraphobic cognitions (Agoraphobic Cognitions Questionnaire) or avoidance behavior (Mobility Inventory Avoidance Scale) was examined by multiple linear regression analyses adjusted for sex, level of education, duration of illness, comorbid psychopathology, and baseline severity. The interaction between personality and age was examined among those treated with CBT (n=90); the interaction between personality and treatment modality was examined among the older subgroup (n=34). Results: Cluster B personality pathology (evaluated on the basis of either Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised (DSM-III-R) or Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) criteria depending on the date of assessment) was negatively associated with outcomes of CBT in both younger and older adults with panic disorder and agoraphobia. Older adults with a higher number of features of any personality pathology or cluster A pathology had worse treatment outcomes when treated with paroxetine compared with CBT. Conclusions: Cluster B pathology had a detrimental effect on CBT treatment outcome for panic disorder in both age groups. In late-life panic disorder with comorbid personality pathology, CBT may be preferred over treatment with paroxetine. 11 p. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1527-4160 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7ff4099bc6b14f08d00ecd27802f0b https://doi.org/10.1097/PRA.0000000000000472 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....ba7ff4099bc6b14f08d00ecd27802f0b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15274160 |
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