Impact of very preterm birth and post-discharge growth on cardiometabolic outcomes at school age: a retrospective cohort study
| العنوان: | Impact of very preterm birth and post-discharge growth on cardiometabolic outcomes at school age: a retrospective cohort study |
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| المؤلفون: | In Gyu Song, Choong Ho Shin, Jungha Yun, Young Ah Lee, Ee Kyung Kim, Young Hwa Jung, Seung Han Shin, Han Suk Kim |
| المصدر: | BMC Pediatrics, Vol 21, Iss 1, Pp 1-9 (2021) BMC Pediatrics |
| بيانات النشر: | BMC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Post discharge, media_common.quotation_subject, Aftercare, Growth, Pediatrics, RJ1-570, Young Adult, Pregnancy, medicine, Humans, Infant, Very Low Birth Weight, Very Preterm Birth, Child, Retrospective Studies, media_common, Schools, School age child, business.industry, Research, Infant, Newborn, Infant, Health technology, Retrospective cohort study, Insulin resistance, Patient Discharge, Very preterm infants, Cardiovascular Diseases, Family medicine, Pediatrics, Perinatology and Child Health, Hypertension, Premature Birth, Female, Christian ministry, business, Welfare, Infant, Premature |
| الوصف: | BackgroundAdverse metabolic outcomes later in life have been reported among children or young adults who were born as preterm infants. This study was conducted to examine the impact of very preterm/very low birth weight (VP/VLBW) birth and subsequent growth after hospital discharge on cardiometabolic outcomes such as insulin resistance, fasting glucose, and systolic and diastolic blood pressure (BP) among children at 6–8 years of age.MethodsThis retrospective cohort study included children aged 6–8 years and compared those who were born at n = 60) with those born at term (n = 110). Body size, fat mass, BP, glucose, insulin, leptin, adiponectin, and lipid profiles were measured. Weight-for-age z-score changes between discharge and early school-age period were also calculated, and factors associated with BP, fasting glucose, and insulin resistance were analyzed.ResultsChildren who were born VP/VLBW had significantly lower fat masses, higher systolic BP and diastolic BP, and significantly higher values of fasting glucose, insulin, and homeostatic model assessment of insulin resistance (HOMA-IR), compared to children born at term. VP/VLBW was correlated with HOMA-IR and BPs after adjusting for various factors, including fat mass index and weight-for-age z-score changes. Weight-for-age z-score changes were associated with HOMA-IR, but not with BPs.ConclusionsAlthough children aged 6–8 years who were born VP/VLBW showed significantly lower weight and fat mass, they had significantly higher BPs, fasting glucose, HOMA-IR, and leptin levels. The associations of VP/VLBW with cardiometabolic factors were independent of fat mass and weight gain velocity. |
| اللغة: | English |
| تدمد: | 1471-2431 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb92acf80e396f08dc6c7f4f786fba16 https://doaj.org/article/cd44eb0f0bde4bf8b7bd900f22ca54d6 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....bb92acf80e396f08dc6c7f4f786fba16 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14712431 |
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