Diabetes and impaired glucose metabolism is associated with more cold-related cardiorespiratory symptoms

التفاصيل البيبلوغرافية
العنوان: Diabetes and impaired glucose metabolism is associated with more cold-related cardiorespiratory symptoms
المؤلفون: Leena Moilanen, Pekka Jousilahti, Markku Peltonen, Liisa Hiltunen, Jari Jokelainen, Tiina M. Ikäheimo, Tiina Laatikainen, Sirkka Keinänen-Kiukaanniemi, Juhani Hassi, Simo Näyhä, Juha Saltevo
المساهمون: School of Medicine / Public Health
بيانات النشر: Elsevier BV, 2017.
سنة النشر: 2017
مصطلحات موضوعية: Blood Glucose, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Population, 030209 endocrinology & metabolism, Type 2 diabetes, Chest pain, Impaired glucose tolerance, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Impaired glucose metabolism, Risk Factors, Internal medicine, Diabetes mellitus, Glucose Intolerance, Internal Medicine, medicine, Humans, 030212 general & internal medicine, education, Aged, education.field_of_study, business.industry, Cold temperature, Diabetes, Cardiorespiratory fitness, General Medicine, Glucose Tolerance Test, Middle Aged, medicine.disease, Impaired fasting glucose, Cold Temperature, Diabetes Mellitus, Type 2, Cardiovascular Diseases, Symptoms, Population study, Female, medicine.symptom, business
الوصف: Aims Diabetes and impaired glucose metabolism cause metabolic, neural and circulatory disturbances that may predispose to adverse cooling and related symptoms during the cold season. This study assessed the prevalence of cold-related cardiorespiratory symptoms in the general population according to glycaemic status. Methods The study population consisted of 2436 men and 2708 women aged 45–74 years who participated in the National FINRISK cold sub-studies in 2002 and 2007. A questionnaire assessed cold-related symptoms (respiratory, cardiac, peripheral circulation). Glycaemic status was determined based on fasting blood glucose, oral glucose tolerance tests or reported diagnosis of diabetes and categorized into normal glucose metabolism, impaired fasting blood glucose, impaired glucose tolerance, screening-detected type 2 diabetes and type 2 diabetes. Results Type 2 diabetes was associated with increased odds for cold-related dyspnoea [Adjusted OR 1.72 (95% CI, 1.28–2.30)], chest pain [2.10 (1.32–3.34)] and respiratory symptoms [1.85 (1.44–2.38)] compared with normal glucose metabolism. Screened type 2 diabetes showed increased OR for cold-related dyspnoea [1.36 (1.04–1.77)], cough [1.41 (1.06–1.87)] and cardiac symptoms [1.51 (1.04–2.20)]. Worsening of glycaemic status was associated with increased odds for cold-related dyspnoea (from 1.16 in impaired fasting glucose to 1.72 in type 2 diabetes, P = 0.000), cough (1.02–1.27, P = 0.032), chest pain (1.28–2.10, P = 0.006), arrhythmias (0.87–1.74, P = 0.020), cardiac (1.11–1.99, P = 0.000), respiratory (1.14–1.84, P = 0.000) and all symptoms (1.05–1.66, P = 0.003). Conclusions Subjects with diabetes and pre-diabetes experience more cold-related cardiorespiratory symptoms and need instructions for proper protection from cold weather to reduce adverse health effects.
final draft
peerReviewed
اللغة: English
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb964b357f2728c91c793da1fc133486
https://erepo.uef.fi/handle/123456789/2644
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....bb964b357f2728c91c793da1fc133486
قاعدة البيانات: OpenAIRE