Diversity of cultivable fungal endophytes in Paullinia cupana (Mart.) Ducke and bioactivity of their secondary metabolites
| العنوان: | Diversity of cultivable fungal endophytes in Paullinia cupana (Mart.) Ducke and bioactivity of their secondary metabolites |
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| المؤلفون: | Elisabeth Aparecida Furtado de Mendonça, Érica de Melo Reis, Olívia Moreira Sampaio, Ana Paula de Araújo Boleti, Marcos Antônio Soares, Marilene Borges Silva Passos, Ana Helena Januário, Edson Lucas dos Santos, Rhavena Graziela Liotti, Carmen Lucia Bassi Branco, Gilvan Ferreira da Silva, Fábio de Azevedo Silva |
| المصدر: | PLoS ONE, Vol 13, Iss 4, p e0195874 (2018) PLoS ONE |
| بيانات النشر: | Public Library of Science (PLoS), 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | 0301 basic medicine, Fungal Structure, Secondary Metabolism, lcsh:Medicine, Plant Science, Diaporthe phaseolorum, medicine.disease_cause, Pathology and Laboratory Medicine, Plant Roots, Medicine and Health Sciences, Endophytes, Paullinia, Cluster Analysis, lcsh:Science, Pathogen, Fungal Pathogens, Multidisciplinary, Geography, Ecology, Antimicrobials, Plant Anatomy, Eukaryota, Drugs, Biodiversity, Phylogeography, Biogeography, Community Ecology, Medical Microbiology, Seeds, Metabolome, Pathogens, Research Article, Ecological Metrics, Mycology, CHO Cells, Biology, Microbiology, 03 medical and health sciences, food, Cricetulus, Quantitative Trait, Heritable, Microbial Control, Botany, medicine, Genetics, Paullinia cupana, Animals, Metabolomics, Microbiome, Secondary metabolism, Microbial Pathogens, Community Structure, Pharmacology, Evolutionary Biology, Population Biology, Pseudomonas aeruginosa, Host (biology), Ecology and Environmental Sciences, lcsh:R, Organisms, Fungi, Species diversity, Biology and Life Sciences, Species Diversity, biology.organism_classification, food.food, 030104 developmental biology, Earth Sciences, Antibacterials, lcsh:Q, Population Genetics |
| الوصف: | Paullinia cupana is associated with a diverse community of pathogenic and endophytic microorganisms. We isolated and identified endophytic fungal communities from the roots and seeds of P. cupana genotypes susceptible and tolerant to anthracnose that grow in two sites of the Brazilian Amazonia forest. We assessed the antibacterial, antitumor and genotoxic activity in vitro of compounds isolated from the strains Trichoderma asperellum (1BDA) and Diaporthe phaseolorum (8S). In concert, we identified eight fungal species not previously reported as endophytes; some fungal species capable of inhibiting pathogen growth; and the production of antibiotics and compounds with bacteriostatic activity against Pseudomonas aeruginosa in both susceptible and multiresistant host strains. The plant genotype, geographic location and specially the organ influenced the composition of P. cupana endophytic fungal community. Together, our findings identify important functional roles of endophytic species found within the microbiome of P. cupana. This hypothesis requires experimental validation to propose management of this microbiome with the objective of promoting plant growth and protection. |
| اللغة: | English |
| تدمد: | 1932-6203 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd1aa0c850bb04efd33f7e3cb6883bf9 http://europepmc.org/articles/PMC5897019?pdf=render |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....bd1aa0c850bb04efd33f7e3cb6883bf9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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