Trifecta and Pentafecta Rates After Robotic Assisted Partial Nephrectomy: Comparative Study of Patients with Renal Masses <4 and ≥4 cm
| العنوان: | Trifecta and Pentafecta Rates After Robotic Assisted Partial Nephrectomy: Comparative Study of Patients with Renal Masses <4 and ≥4 cm |
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| المؤلفون: | Fabio Neri, Michele Marchioni, Francesco Berardinelli, Giulia Primiceri, Luca Cindolo, Roberto Castellucci, Luigi Schips, Carlo D'Orta, Pietro Castellan |
| المصدر: | Journal of Laparoendoscopic & Advanced Surgical Techniques. 28:799-803 |
| بيانات النشر: | Mary Ann Liebert Inc, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Databases, Factual, genetic structures, Robotic assisted, medicine.medical_treatment, 030232 urology & nephrology, Nephrectomy, 03 medical and health sciences, Postoperative Complications, 0302 clinical medicine, Robotic Surgical Procedures, medicine, Renal mass, Humans, Robotic surgery, In patient, Warm Ischemia, Aged, Retrospective Studies, business.industry, Margins of Excision, Middle Aged, medicine.disease, Kidney Neoplasms, Tumor Burden, Surgery, Treatment Outcome, 030220 oncology & carcinogenesis, Disease Progression, Feasibility Studies, Female, business, human activities, Kidney cancer, Glomerular Filtration Rate |
| الوصف: | Robotic-assisted partial nephrectomy (RAPN) is preferred to radical nephrectomy because it guarantees superior functional outcomes in patients with small renal masses (RMs). Only a few studies so far have evaluated the feasibility of RAPN for the treatment of RM ≥4 cm. The aim of this study is to evaluate the safety and feasibility of RAPN based on a comparison of trifecta and pentafecta rates for RMs ≥4 cm.We retrospectively analyzed prospectively collected data from an institutional database of patients undergoing RAPN from September 2013 to November 2016. Demographic and perioperative data were collected and statistically analyzed. Pentafecta is defined as achievement of trifecta (negative surgical margins, no postoperative complications, and warm ischemia time ≤25 minutes) with the addition of two other variables, namely, over 90% estimated glomerular filtration rate preservation and no chronic kidney disease stage progression 1 year after surgery.Overall, 123 patients underwent RAPN. Of those, 38 (30.9%) had RMs ≥4 cm. Trifecta was achieved in 72.9% of patients with RMs4 cm and in 44.7% of those with ≥4 cm, whereas pentafecta was achieved by 23.5% of patients with RMs4 cm and by 10.5% of those with RMs ≥4 cm. No significant predictive factors were found in connection with trifecta, whereas only one was found in connection with pentafecta, namely, age (odds ratio: 0.91; 95% confidence interval 0.85-0.98; P = .01).RAPN may be considered a feasible and safe surgical approach ensuring good functional outcome even for patients with RMs ≥4 cm. Pentafecta rates after RAPN were comparable between RMs4 and ≥4 cm in diameter. |
| تدمد: | 1557-9034 1092-6429 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8aad2416333e690934432f25281c60 https://doi.org/10.1089/lap.2017.0657 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....bd8aad2416333e690934432f25281c60 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15579034 10926429 |
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