Low incidence of choroidal neovascularization following subthreshold diode micropulse laser (SDM) in high-risk AMD
| العنوان: | Low incidence of choroidal neovascularization following subthreshold diode micropulse laser (SDM) in high-risk AMD |
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| المؤلفون: | Solly Elmann, Stephen H. Sinclair, Jeffrey K. Luttrull, Bert M. Glaser |
| المصدر: | PLoS ONE PLoS ONE, Vol 13, Iss 8, p e0202097 (2018) |
| بيانات النشر: | Public Library of Science, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | 0301 basic medicine, Male, Visual acuity, genetic structures, Eye Diseases, Physiology, Vision, Visual Acuity, lcsh:Medicine, Social Sciences, Blood Pressure, Comorbidity, Kaplan-Meier Estimate, Cardiovascular Physiology, Vascular Medicine, Macular Degeneration, 0302 clinical medicine, Risk Factors, Vasculogenesis, Clinical endpoint, Medicine and Health Sciences, Morphogenesis, Psychology, Geriatric Ophthalmology, lcsh:Science, Aged, 80 and over, Multidisciplinary, Incidence (epidemiology), Incidence, Retinal Degeneration, Choroidal neovascularization, Optical Equipment, Hypertension, Retinal Disorders, Engineering and Technology, Diode Lasers, Sensory Perception, Female, Laser Therapy, medicine.symptom, Anatomy, After treatment, Research Article, medicine.medical_specialty, Equipment, Risk Assessment, 03 medical and health sciences, Ocular System, Ophthalmology, medicine, Effective treatment, Humans, Aged, business.industry, Lasers, lcsh:R, Biology and Life Sciences, Retrospective cohort study, Macular degeneration, medicine.disease, eye diseases, Choroidal Neovascularization, 030104 developmental biology, Geriatrics, Macular Disorders, 030221 ophthalmology & optometry, Eyes, lcsh:Q, sense organs, business, Head, Developmental Biology, Neuroscience, Follow-Up Studies |
| الوصف: | PURPOSE To determine the incidence of new choroidal neovascularization (CNV) in eyes with dry age-related macular degeneration (AMD) following subthreshold diode micropulse laser (SDM). METHOD In an observational retrospective cohort study, the records of all patients active in the electronic medical records database were reviewed to identify eyes with dry AMD treated with SDM. Identified eyes were classified by simplified AREDS categories, and analyzed for the primary endpoint of new CNV after treatment. RESULTS The EMR revealed SDM was offered to 373/392 (95%) patients with dry AMD and elected by 363/373 (97%) between 2008-2017. Follow up was available for 354/363 patients (547 eyes, 98%) (range 6-108 mos., avg. 22). CNV risk factors included age (median 84 years, 67% > 80); reticular pseudodrusen (214 eyes, 39%); AREDS category (78% category 3 and 4); and fellow eye CNV (128 eyes, 23%). New CNV developed in 9/547 eyes (1.6%, annualized rate 0.87%). Visual acuity was unchanged. There were no adverse treatment effects. SUMMARY In a review of a large group of eyes with exceptionally high-risk AMD, SDM was followed by a very low incidence of new CNV. If confirmed by further study, SDM would offer a new and highly effective treatment to reduce the risk of vision loss from AMD. |
| اللغة: | English |
| تدمد: | 1932-6203 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1873229dcd9b9f85fe5dee775ffd78 http://europepmc.org/articles/PMC6107149 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....be1873229dcd9b9f85fe5dee775ffd78 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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