Isolation and Caenorhabditis elegans Lifespan Assay of Flavonoids from Onion
| العنوان: | Isolation and Caenorhabditis elegans Lifespan Assay of Flavonoids from Onion |
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| المؤلفون: | Kazuo Furihata, Tomoyuki Ahiko, Hisako Amino, You-Lin Xue, Takuji Shirasawa, Takuya Miyakawa, Yoriko Sawano, Kiyoshi Kita, Masaru Tanokura, Fangyu Hu |
| المصدر: | Journal of Agricultural and Food Chemistry. 59:5927-5934 |
| بيانات النشر: | American Chemical Society (ACS), 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Antioxidant, DPPH, medicine.medical_treatment, Longevity, Flavonoid, Antioxidants, chemistry.chemical_compound, Life Expectancy, Onions, medicine, Animals, heterocyclic compounds, Caenorhabditis elegans, Legume, Flavonoids, chemistry.chemical_classification, biology, Plant Extracts, Liliaceae, fungi, food and beverages, General Chemistry, biology.organism_classification, chemistry, Biochemistry, Polyphenol, General Agricultural and Biological Sciences, Quercetin |
| الوصف: | The main flavonoids were isolated from three selected onion cultivars. Three phenolic compounds were obtained by reverse-phase HPLC, and their structures were elucidated by multiple NMR measurements. There were two known compounds, quercetin and quercetin 3'-O-β-D-glucopyranoside (Q3'G), and one novel compound, quercetin 3-O-β-D-glucopyranoside-(4→1)-β-d-glucopyranoside (Q3M), which was identified in onion for the first time. These flavonoids were found to be more abundant in the onion peel than in the flesh or core. Their antioxidative activities were tested using the DPPH method, and their antiaging activities were evaluated using a Caenorhabditis elegans lifespan assay. No direct correlation was found between antioxidative activity and antiaging activity. Quercetin showed the highest antioxidative activity, whereas Q3M showed the strongest antiaging activity among these flavonoids, which might be related to its high hydrophilicity. |
| تدمد: | 1520-5118 0021-8561 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be277d8951bbc637d5c8e1e4c4a492f5 https://doi.org/10.1021/jf104798n |
| رقم الأكسشن: | edsair.doi.dedup.....be277d8951bbc637d5c8e1e4c4a492f5 |
| قاعدة البيانات: | OpenAIRE |
Find this issue from the American Chemical Society | تدمد: | 15205118 00218561 |
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