Comparative in vitro antibacterial activity of ozenoxacin against Gram-positive clinical isolates
| العنوان: | Comparative in vitro antibacterial activity of ozenoxacin against Gram-positive clinical isolates |
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| المؤلفون: | Ian Morrissey, Jordi Vila, María García-Castillo, Domingo Gargallo-Viola, Ilonka Zsolt, Marta Tato, Yuly López, Rafael Cantón |
| المساهمون: | Universitat de Barcelona |
| المصدر: | Dipòsit Digital de la UB Universidad de Barcelona Recercat. Dipósit de la Recerca de Catalunya instname |
| بيانات النشر: | Future Medicine Ltd, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | 0301 basic medicine, Microbiology (medical), Staphylococcus aureus, Streptococcus pyogenes, Bacterial diseases, 030106 microbiology, Aminopyridines, Levofloxacin, Microbial Sensitivity Tests, Quinolones, Biology, medicine.disease_cause, Impetigo, Staphylococcaceae, Microbiology, Streptococcus agalactiae, Methicillin, 03 medical and health sciences, medicine, Humans, Malalties bacterianes, Broth microdilution, Antimicrobial, Anti-Bacterial Agents, Skin diseases, Malalties de la pell, Ozenoxacin, Methicillin Resistance, Antibacterial activity, medicine.drug |
| الوصف: | Aim: To compare the in vitro activity of the anti-impetigo agent, ozenoxacin, and other antimicrobial agents against Gram-positive clinical isolates from skin and soft tissue infections. Materials & methods: Isolates were collected in two studies: 1097 isolates from 49 centers during 2009–2010 and 1031 isolates from ten centers during 2014. Minimum inhibitory concentrations were determined for 18 and 11 antimicrobials in these studies, respectively, using standard broth microdilution methods. Isolates were stratified by species and methicillin susceptibility/resistance and/or levofloxacin susceptibility/nonsusceptibility status. Results: Ozenoxacin exhibited high in vitro activity against Staphylococcus aureus and coagulase-negative staphylococci isolates in both studies. Ozenoxacin was also highly active against Streptococcus pyogenes and Streptococcus agalactiae isolates. Conclusion: Ozenoxacin is a potent antimicrobial agent against staphylococci and streptococci. |
| وصف الملف: | application/pdf |
| تدمد: | 1746-0921 1746-0913 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8d281625d5163613e0da45cb399e11 https://doi.org/10.2217/fmb-2017-0289 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....be8d281625d5163613e0da45cb399e11 |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 17460921 17460913 |
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