Evaluation of non-invasive imaging parameters in coronary microvascular disease: a systematic review
| العنوان: | Evaluation of non-invasive imaging parameters in coronary microvascular disease: a systematic review |
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| المؤلفون: | Groepenhoff, F, Klaassen, RGM, Valstar, GB, Bots, SH, Onland-Moret, NC, Den, Ruijter HM, Leiner, T, Eikendal, ALM, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology |
| المساهمون: | Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Oncology |
| المصدر: | BMC Medical Imaging, Vol 21, Iss 1, Pp 1-23 (2021) BMC Medical Imaging BMC Medical Imaging, 21(1), 1. BioMed Central BMC medical imaging, 21(1):5. BioMed Central |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Noninvasive imaging, lcsh:Medical technology, Coronary flow reserve, Coronary Artery Disease, 030204 cardiovascular system & hematology, 030218 nuclear medicine & medical imaging, Angina Pectoris, Reference values, Angina, 03 medical and health sciences, 0302 clinical medicine, Sex Factors, Coronary Circulation, Non-invasive imaging, DIAGNOSTIC STANDARD, Medicine, Humans, Coronary microvascular dysfunction, Radiology, Nuclear Medicine and imaging, medicine.diagnostic_test, business.industry, Microcirculation, Correction, Coronary Microvascular Disease, medicine.disease, Coronary arteries, medicine.anatomical_structure, Myocardial perfusion reserve, lcsh:R855-855.5, Positron emission tomography, Echocardiography, Radiology Nuclear Medicine and imaging, Positron-Emission Tomography, Radiology, business, Magnetic Resonance Angiography, Research Article |
| الوصف: | Background Coronary microvascular dysfunction (CMD) is an important underlying cause of angina pectoris. Currently, no diagnostic tool is available to directly visualize the coronary microvasculature. Invasive microvascular reactivity testing is the diagnostic standard for CMD, but several non-invasive imaging techniques are being evaluated. However, evidence on reported non-invasive parameters and cut-off values is limited. Thus, we aimed to provide an overview of reported non-invasive parameters and corresponding cut-off values for CMD. Methods Pubmed and EMBASE databases were systematically searched for studies enrolling patients with angina pectoris without obstructed coronary arteries, investigating at least one non-invasive imaging technique to quantify CMD. Methodological quality assessment of included studies was performed using QUADAS-2. Results Thirty-seven studies were included. Ten cardiac magnetic resonance studies reported MPRI and nine positron emission tomography (PET) and transthoracic echocardiography (TTE) studies reported CFR. Mean MPRI ranged from 1.47 ± 0.36 to 2.01 ± 0.41 in patients and from 1.50 ± 0.47 to 2.68 ± 0.49 in controls without CMD. Reported mean CFR in PET and TTE ranged from 1.39 ± 0.31 to 2.85 ± 1.35 and 1.69 ± 0.40 to 2.40 ± 0.40 for patients, and 2.68 ± 0.83 to 4.32 ± 1.78 and 2.65 ± 0.65 to 3.31 ± 1.10 for controls, respectively. Conclusions This systematic review summarized current evidence on reported parameters and cut-off values to diagnose CMD for various non-invasive imaging modalities. In current clinical practice, CMD is generally diagnosed with a CFR less than 2.0. However, due to heterogeneity in methodology and reporting of outcome measures, outcomes could not be compared and no definite reference values could be provided. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1471-2342 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf2acf678a82b76128f5045ae1a14dc3 https://doi.org/10.1186/s12880-020-00535-7 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....bf2acf678a82b76128f5045ae1a14dc3 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14712342 |
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