Pilot study to assess the effects of early flea exposure on the development of flea hypersensitivity in cats
| العنوان: | Pilot study to assess the effects of early flea exposure on the development of flea hypersensitivity in cats |
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| المؤلفون: | D.B Logas, A Pilny, C Nicklin, C.A McCall, K.E Stedman, Gail A. Kunkle |
| المصدر: | Journal of Feline Medicine and Surgery. 5:287-294 |
| بيانات النشر: | SAGE Publications, 2003. |
| سنة النشر: | 2003 |
| مصطلحات موضوعية: | Male, Saliva, Flea, Flea allergy dermatitis, animal diseases, Enzyme-Linked Immunosorbent Assay, Pilot Projects, Ectoparasitic Infestations, Cat Diseases, Immunoglobulin E, medicine, Animals, Hypersensitivity, Delayed, Small Animals, Sensitization, CATS, biology, Incidence (epidemiology), Significant difference, Intradermal Tests, bacterial infections and mycoses, medicine.anatomical_structure, Animals, Newborn, Dermatitis, Allergic Contact, Immunology, Cats, biology.protein, Siphonaptera, Female |
| الوصف: | This pilot study was to determine if early oral flea exposure reduces the incidence of flea allergy dermatitis (FAD) in cats. Eighteen kittens, assigned to three groups, received no flea exposure, oral flea exposure or flea infestation for 12 weeks. Then all the kittens were exposed continually to fleas for 31 weeks. Sensitization was monitored using intradermal testing (IDT), in vitro measurement of anti-flea saliva immunoglobulin E (IgE) and development of FAD. There was no statistically significant difference between groups in IDT reactions, in vitro data or clinical scores. The development of FAD was not associated with the presence of anti-flea saliva IgE. However, the development of a delayed reaction to flea bite was associated with symptoms after flea exposure. Although not statistically significant, the FAD scores in the oral group were lower than in the controls. Further studies are required to determine the role of oral flea exposure in the development of FAD in cats. |
| تدمد: | 1532-2750 1098-612X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf4ed1ccc596032da5e2fdab78a255fd https://doi.org/10.1016/s1098-612x(03)00026-3 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....bf4ed1ccc596032da5e2fdab78a255fd |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15322750 1098612X |
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