Elevated serum triglyceride predicts recurrence of colorectal polyps in patients with advanced adenomas
| العنوان: | Elevated serum triglyceride predicts recurrence of colorectal polyps in patients with advanced adenomas |
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| المؤلفون: | Pingwu Wen, Boying Liu, Ruiqiang Weng, Sudong Liu, Xiaodong Gu |
| المصدر: | Lipids in Health and Disease Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-8 (2020) |
| بيانات النشر: | BioMed Central, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Male, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Colonoscopy, Gastroenterology, Triglyceride, 0302 clinical medicine, Endocrinology, Risk Factors, Recurrence, Odds Ratio, lcsh:RC620-627, medicine.diagnostic_test, biology, Middle Aged, Prognosis, Lipid profile, lcsh:Nutritional diseases. Deficiency diseases, surgical procedures, operative, 030220 oncology & carcinogenesis, 030211 gastroenterology & hepatology, Apolipoprotein A1, Female, Colorectal Neoplasms, Adenoma, medicine.medical_specialty, Colon, Colonic Polyps, 03 medical and health sciences, Internal medicine, medicine, otorhinolaryngologic diseases, Humans, Colorectal polyp, Risk factor, neoplasms, Triglycerides, Aged, Neoplasm Staging, Retrospective Studies, Apolipoprotein A-I, business.industry, Research, Biochemistry (medical), Cholesterol, HDL, Odds ratio, Cholesterol, LDL, medicine.disease, Confidence interval, digestive system diseases, Logistic Models, Colorectal Polyp, biology.protein, business, Biomarkers |
| الوصف: | Background Recurrence of colorectal polyps is common and impacted by various factors. This study was performed to explore the association between lipid profiles and recurrence of colorectal polyps. Methods This study retrospectively analyzed the lipid profiles of 435 patients who underwent colonoscopy with removal of colorectal polyps and assessed recurrence of polyps by follow-up colonoscopy. Multivariate regression logistic analysis was used to evaluate the association between lipid profiles and polyp recurrence. Results During the 1.5-year follow-up, recurrence of colorectal polyps was observed in 135 of 435 patients (30.34%). Patients with recurrent polyps showed a higher level of triglycerides (P = 0.006) and lower levels of high-density lipoprotein cholesterol (P = 0.008) and apolipoprotein A1 (P = 0.033). The multivariate regression logistic model suggested that an elevated triglyceride level was an independent risk factor for polyp recurrence (odds ratio, 1.55; 95% confidence interval, 1.02–2.35; P = 0.039) in patients with advanced adenoma. Conclusions Lipid profiles are associated with recurrence of colorectal polyps. An elevated triglyceride level is an independent risk predictor of polyp recurrence in patients with advanced adenoma. |
| اللغة: | English |
| تدمد: | 1476-511X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf93d12744d7e69db485868610198a46 http://europepmc.org/articles/PMC7513493 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....bf93d12744d7e69db485868610198a46 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 1476511X |
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