Cigarette Smoking Increases Risk of Recurrence for Sinonasal Inverted Papilloma
| العنوان: | Cigarette Smoking Increases Risk of Recurrence for Sinonasal Inverted Papilloma |
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| المؤلفون: | Il Joon Moon, Chul Hee Lee, Yang Gi Min, Doo Hee Han, Doh Young Lee, Myung Whan Suh, Chae Seo Rhee, Seung Tae Kim |
| المصدر: | American Journal of Rhinology & Allergy. 24:325-329 |
| بيانات النشر: | SAGE Publications, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Adult, Male, Nasal cavity, medicine.medical_specialty, Inverted papilloma, Malignancy, Cigarette smoking, Risk Factors, Sinonasal inverted papilloma, Humans, Immunology and Allergy, Medicine, Aged, Neoplasm Staging, Proportional Hazards Models, Retrospective Studies, Aged, 80 and over, Papilloma, Inverted, business.industry, Smoking, General Medicine, Middle Aged, medicine.disease, Dermatology, medicine.anatomical_structure, Otorhinolaryngology, Female, Nasal Cavity, Neoplasm Recurrence, Local, business, Paranasal Sinus Neoplasms |
| الوصف: | Background Sinonasal inverted papilloma (IP) is a neoplasm in the nasal cavity, characterized by its local aggressiveness and tendency to cause malignancy. Despite the frequent recurrence of IP, few studies have reported the effects of situational parameters including smoking on the recurrence rate of IP. This study was performed to evaluate clinical and environmental factors including smoking that can predict neoplasm recurrence after surgery in patients with IP. Methods This study was conducted retrospectively on 132 patients who were diagnosed with IP between November 1985 and September 2007. The study focused on the risk factors of recurrence, such as smoking behaviors, diabetes mellitus (DM), hypertension (HTN), allergic rhinitis (AR), the sites of tumor origin and involvement, neoplasm staging, and the surgical method. The age of the patients ranged from 22 to 85 years, and among the 132 patients, 39 patients were smokers (29.5%), 17 (13.3%) with DM, 31 (24.4%) with HTN, and 11 (9.3%) with AR. Results The recurrence rate showed great disparity between the groups of smokers and nonsmokers: 28.2% of smokers suffered recurrence compared with 10.7% recurrence from the nonsmoker group. The Krouse stage IV group experienced more frequent recurrence than the stage I, II, and III groups. Some patients in Krouse stage III (5/72, 6.9%) and IV (3/3, 100%) groups underwent malignant transformation of IP. Histories of DM, HTN, and AR did not exert a statistically meaningful influence on the recurrence and malignant transformation. Conclusion The smoking behavior and tumor with extranasal/sinus extension appear to be associated with recurrence of IP after surgical resection. |
| تدمد: | 1945-8932 1945-8924 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00636d7f51c9ce4ab7c644492282e30 https://doi.org/10.2500/ajra.2010.24.3510 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....c00636d7f51c9ce4ab7c644492282e30 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19458932 19458924 |
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