Intrahepatic cholangiojejunostomy for complex biliary stenosis after pediatric living-donor liver transplantation

التفاصيل البيبلوغرافية
العنوان: Intrahepatic cholangiojejunostomy for complex biliary stenosis after pediatric living-donor liver transplantation
المؤلفون: Rodrigo Sanchez Claria, Fernando A. Alvarez, Martin de Santibañes, Eduardo de Santibañes, Miguel Ciardullo, Juan Pekolj, Juan Glinka
المصدر: Pediatric transplantation. 21(5)
سنة النشر: 2017
مصطلحات موضوعية: Male, medicine.medical_specialty, Percutaneous, medicine.medical_treatment, Cholestasis, Intrahepatic, Anastomosis, Liver transplantation, 03 medical and health sciences, 0302 clinical medicine, Postoperative Complications, Cholestasis, Biliary atresia, medicine, Living Donors, Humans, Retrospective Studies, Transplantation, Bile duct, business.industry, Anastomosis, Surgical, Stent, Infant, medicine.disease, Liver Transplantation, Biliary Tract Surgical Procedures, medicine.anatomical_structure, Bile Ducts, Intrahepatic, Jejunum, Treatment Outcome, 030220 oncology & carcinogenesis, Child, Preschool, Pediatrics, Perinatology and Child Health, 030211 gastroenterology & hepatology, Female, Radiology, business, Follow-Up Studies
الوصف: The treatment of biliary stenosis after pediatric LDLT is challenging. We describe an innovative technique of peripheral IHCJ for the treatment of patients with complex biliary stenosis after pediatric LDLT in whom percutaneous treatment failed. During surgery, the percutaneous biliary drainage is removed and a flexible metal stylet is introduced trough the tract. Subsequently, the most superficial aspect of the biliary tree is recognized by palpation of the stylet's round tip in the liver surface. The liver parenchyma is then transected until the bile duct is reached. A side-to-side anastomosis to the previous Roux-en-Y limb is performed over a silicone stent. Among 328 pediatric liver transplants performed between 1988 and 2015, 26 patients developed biliary stenosis. From nine patients requiring surgery, three patients who had received left lateral grafts from living-related donors due to biliary atresia were successfully treated with IHCJ. After a mean of 45.6 months, all patients are alive with normal liver morphological and function tests. The presented technique was a feasible and safe surgical option to treat selected pediatric recipients with complex biliary stenosis in whom percutaneous procedures or rehepaticojejunostomy were not possible, allowing complete resolution of cholestasis and thus avoiding liver retransplantation.
تدمد: 1399-3046
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f07ce73a96226dee9cc7fba069daa0
https://pubmed.ncbi.nlm.nih.gov/28497648
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....c0f07ce73a96226dee9cc7fba069daa0
قاعدة البيانات: OpenAIRE