Prevalence of co-existing autoimmune disease in juvenile idiopathic arthritis: a cross-sectional study
| العنوان: | Prevalence of co-existing autoimmune disease in juvenile idiopathic arthritis: a cross-sectional study |
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| المؤلفون: | Gowri Priya Harikrishnan, Hugh Kawabata, Daniel J. Lovell, Teresa A. Simon, Hermine I. Brunner, Sanket Singhal |
| المصدر: | Pediatric Rheumatology Online Journal, Vol 18, Iss 1, Pp 1-12 (2020) Pediatric Rheumatology Online Journal |
| بيانات النشر: | BMC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Male, 0301 basic medicine, lcsh:Diseases of the musculoskeletal system, Cross-sectional study, Epidemiology, Comorbidity, 0302 clinical medicine, Crohn Disease, Odds Ratio, Prevalence, Immunology and Allergy, Chronic Urticaria, Child, lcsh:RJ1-570, Middle Aged, Sjogren's Syndrome, Female, Diagnosis code, Research Article, Adult, medicine.medical_specialty, Adolescent, Alopecia Areata, Autoimmune Diseases, Uveitis, Young Adult, 03 medical and health sciences, Rheumatology, Internal medicine, Sicca syndrome, medicine, Humans, ADHD, Retrospective Studies, 030203 arthritis & rheumatology, Autoimmune disease, Scleroderma, Systemic, business.industry, Thyroiditis, Autoimmune, Co-existing autoimmune disease, lcsh:Pediatrics, Odds ratio, Juvenile idiopathic arthritis, medicine.disease, Arthritis, Juvenile, Cross-Sectional Studies, 030104 developmental biology, Case-Control Studies, Pediatrics, Perinatology and Child Health, lcsh:RC925-935, business |
| الوصف: | Background Many autoimmune diseases share common pathogenic mechanisms, cytokine pathways and systemic inflammatory cascades; however, large studies quantifying the co-existence of autoimmune diseases in patients with juvenile idiopathic arthritis (JIA) have not been conducted. Methods We performed a cross-sectional study using two United States administrative healthcare claims databases (Truven Health MarketScan® Commercial Database and IMS PharMetrics database) to screen for the prevalence of multiple autoimmune diseases in patients with JIA and in a control group with attention deficit hyperactivity disorder (ADHD). Patients with a diagnosis code for JIA or ADHD between January 1, 2006 and September 30, 2017 were separated into two age cohorts ( Results Overall, 29,215 patients with JIA and 134,625 matched control patients with ADHD were evaluated. Among patients in the MarketScan database, 28/30 autoimmune diseases were more prevalent in patients with JIA aged Conclusions Patients with JIA are more likely to have concurrent autoimmune diseases than matched patients with ADHD. Having an awareness of the co-existence of autoimmune diseases among patients with JIA may play an important role in patient management, treatment decisions, and outcomes. Trial registration Not applicable. |
| اللغة: | English |
| تدمد: | 1546-0096 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15a35bb4c1e62fe2fe9493d7c7c62db http://link.springer.com/article/10.1186/s12969-020-00426-9 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....c15a35bb4c1e62fe2fe9493d7c7c62db |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 15460096 |
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