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Antibody response to second dose of the BNT162b2 mRNA vaccine in the first 12 weeks in South Korea: A prospective longitudinal study

التفاصيل البيبلوغرافية
العنوان: Antibody response to second dose of the BNT162b2 mRNA vaccine in the first 12 weeks in South Korea: A prospective longitudinal study
المؤلفون: Hyun Jin Kim, Heon Jeong Yun, Jungok Kim, Sungmin Kym, Qute Choi
المصدر: Vaccine
سنة النشر: 2021
مصطلحات موضوعية: Vaccines, Synthetic, General Veterinary, General Immunology and Microbiology, SARS-CoV-2, Public Health, Environmental and Occupational Health, COVID-19, Antibodies, Viral, Article, Infectious Diseases, Antibody Formation, Antibody response, Molecular Medicine, Humans, Severe acute respiratory syndrome coronavirus 2, BNT162b2, Longitudinal Studies, Prospective Studies, mRNA Vaccines, BNT162 Vaccine, Receptor binding domain
الوصف: Objectives To characterise the antibody response for 12 weeks following second dose of the Pfizer/BioNTech BNT162b2 mRNA vaccine in hospital workers of a Korean general hospital. Methods We measured the level of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) anti-receptor binding domain (anti-RBD) and neutralising antibodies every week in the first 4 weeks, and at weeks 8 and 12 following the second dose of vaccination in 71 hospital workers. Results The initial median level of anti-RBD and neutralising antibodies were 3898.0 U/mL (interquartile range [IQR], 2107.5–5478.5) and 97.54 % (IQR, 96.85–97.81), respectively. The levels declined the fastest and the most significantly between weeks 1 and 2 (p
تدمد: 1873-2518
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ec908aec506637c2f139144db6a450
https://pubmed.ncbi.nlm.nih.gov/34953606
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....c1ec908aec506637c2f139144db6a450
قاعدة البيانات: OpenAIRE
الوصف
تدمد:18732518