Pharmacological safety during pregnancy: the principles of teratogenesis and teratogenicity of drugs

التفاصيل البيبلوغرافية
العنوان: Pharmacological safety during pregnancy: the principles of teratogenesis and teratogenicity of drugs
المؤلفون: O. V. Reshet’ko, K. A. Lutsevich, N. I. Klimenchenko
المصدر: Pediatričeskaâ Farmakologiâ, Vol 13, Iss 2, Pp 105-115 (2016)
بيانات النشر: Paediatrician Publishers LLC, 2016.
سنة النشر: 2016
مصطلحات موضوعية: safety, medicine.medical_specialty, Pregnancy, business.industry, RM1-950, Pharmacology, Drug application, medicine.disease, drugs, birth defects, Family medicine, Pharmacovigilance, Medicine, pregnancy, Therapeutics. Pharmacology, Teratogenic risk, teratogenicity, business, teratogenic mechanisms
الوصف: Drugs used during pregnancy simultaneously have an impact on 2 populations — fetal and maternal. The article is devoted to teratogenic drugs exposition; it points out the need for further research in the field of pharmaceutical safety during pregnancy. Authors analyzed the multiplicity of the congenital disorders in infants, including birth defects cuased by drug application. For ethical reasons, researchers can not conduct any studies on the safety of medicines during pregnancy. Authors suppose that collection of additional information during the marketing phase as a part of the routine pharmacovigilance program and the targeted pharmacoepidemiological trials with the current evaluation of the teratogenic risk of drugs will help to achieve the goals.
تدمد: 1727-5776
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21bbd51ad5367f6be448b33f363f544
https://doi.org/10.15690/pf.v13i2.1551
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....c21bbd51ad5367f6be448b33f363f544
قاعدة البيانات: OpenAIRE