Spotty Calcium on Cervicocerebral Computed Tomography Angiography Associates With Increased Risk of Ischemic Stroke
| العنوان: | Spotty Calcium on Cervicocerebral Computed Tomography Angiography Associates With Increased Risk of Ischemic Stroke |
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| المؤلفون: | Damini Dey, Li Yang, Fan Zhang, Lu Gan, Zhaoyang Fan, Daniel S. Berman, Yibin Xie, Bill Zhou, Zixin Deng, Debiao Li |
| المصدر: | Stroke. 50:859-866 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Advanced and Specialized Nursing, medicine.medical_specialty, medicine.diagnostic_test, business.industry, Carotid ultrasonography, Ischemia, Odds ratio, 030204 cardiovascular system & hematology, medicine.disease, Asymptomatic, Article, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Cardiology, medicine, Clinical significance, Neurology (clinical), medicine.symptom, Cardiology and Cardiovascular Medicine, business, Stroke, 030217 neurology & neurosurgery, Calcification, Computed tomography angiography |
| الوصف: | Background and Purpose— Cervicocerebral vascular calcification on computed tomography angiography is a known sign of advanced atherosclerosis. However, the clinical significance of calcification pattern remains unclear. In this study, we aimed to investigate the potential association between spotty calcium and acute ischemic stroke. Methods— This study included patients with first-time nonlacunar ischemic stroke (N=50) confirmed by brain magnetic resonance imaging or nonenhanced head computed tomography, as well as control subjects with asymptomatic carotid atherosclerosis (N=50) confirmed by carotid ultrasonography. Subjects in both groups underwent contrast-enhanced cervicocerebral computed tomography angiography within a week after the initial imaging examination. Spotty calcification was evaluated at 11 arterial segments commonly affected by atherosclerosis along the carotid and vertebrobasilar circulation. Statistical analysis was performed comparing the frequency and spatial pattern of spotty calcification between the 2 groups. Results— Spotty calcification in the Stroke group was markedly more prevalent than that in the Control group (total SC count: 8.74±4.96 versus 1.84±1.82, P P Conclusions— Nonlacunar ischemia stroke was associated with markedly increased incidence of spotty calcification with a distinct spatial pattern on cervicocerebral computed tomography compared with subclinical atherosclerosis, suggesting the potential role of spotty calcification for improving the risk stratification for ischemic stroke. |
| تدمد: | 1524-4628 0039-2499 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2fba6d8716e503ed9d2470875756c1a https://doi.org/10.1161/strokeaha.118.023273 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....c2fba6d8716e503ed9d2470875756c1a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15244628 00392499 |
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