Impact of New Motor Deficit on HRQOL After Adult Spinal Deformity Surgery:Subanalysis From Scoli Risk 1 Prospective Study
| العنوان: | Impact of New Motor Deficit on HRQOL After Adult Spinal Deformity Surgery:Subanalysis From Scoli Risk 1 Prospective Study |
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| المؤلفون: | Michael G. Fehlings, Hossein Mehdian, Rajiv Saigal, AOSpine Knowledge Forum Deformity, Christopher P Ames, Darryl Lau, Kenneth M.C. Cheung, Sigurd Berven, Yong Qiu, Mark B. Dekutoski, Ferran Pellisé, Leah Y. Carreon, Michael J. Kelly, Yukihiro Matsuyama, Benny Dahl, Lawrence G. Lenke, Christopher I. Shaffrey, Khaled M. Kebaish, Stephen J. Lewis |
| المصدر: | Saigal, R, Lau, D, Berven, S H, Carreon, L, Dekutoski, M B, Kebaish, K M, Qiu, Y, Matsuyama, Y, Kelly, M, Dahl, B T, Mehdian, H, Pellisé, F, Lewis, S J, Cheung, K M C, Shaffrey, C I, Fehlings, M G, Lenke, L G & Ames, C P 2021, ' Impact of New Motor Deficit on HRQOL After Adult Spinal Deformity Surgery : Subanalysis From Scoli Risk 1 Prospective Study ', Spine, vol. 46, no. 7, pp. E450-E457 . https://doi.org/10.1097/BRS.0000000000003852 Spine, vol 46, iss 7 Spine |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, motor deficit, Neurosurgical Procedures, Cohort Studies, 0302 clinical medicine, Postoperative Complications, Quality of life, Deformity, 80 and over, Orthopedics and Sports Medicine, Longitudinal Studies, Prospective Studies, Prospective cohort study, Aged, 80 and over, 030222 orthopedics, Rehabilitation, Middle Aged, humanities, Osteotomy, Motor Skills Disorders, HRQOL, Cohort, Spinal deformity, Spinal Diseases, Female, Patient Safety, medicine.symptom, Adult, medicine.medical_specialty, Adolescent, Clinical Sciences, Biomedical Engineering, AOSpine Knowledge Forum Deformity, 03 medical and health sciences, Young Adult, Clinical Research, medicine, Humans, Retrospective Studies, Aged, business.industry, Background data, adult spinal deformity, Surgery, Brain Disorders, Good Health and Well Being, Orthopedics, Quality of Life, Observational study, Neurology (clinical), business, Motor Deficit, 030217 neurology & neurosurgery |
| الوصف: | An international, multicenter, ambispective, cohort study was completed to study effect of motor deficit on Health-related Quality of Life scores (HRQOLs) after adult spinal deformity surgery. HRQOLs were lower in patients who had more than 2 points of lower extremity motor score worsening. However, even these patients showed overall HRQOL improvement at 2 years. Study Design. International, multicenter, prospective, longitudinal observational cohort. Objective. To assess how new motor deficits affect patient reported quality of life scores after adult deformity surgery. Summary of Background Data. Adult spinal deformity surgery is associated with high morbidity, including risk of new postoperative motor deficit. It is unclear what effect new motor deficit has on Health-related Quality of Life scores (HRQOL) scores. Methods. Adult spinal deformity patients were enrolled prospectively at 15 sites worldwide. Other inclusion criteria included major Cobb more than 80°, C7–L2 curve apex, and any patient undergoing three column osteotomy. American Spinal Injury Association (ASIA) scores and standard HRQOL scores were recorded pre-op, 6 weeks, 6 months, and 2 years. Results. Two hundred seventy two complex adult spinal deformity (ASD) patients enrolled. HRQOL scores were worse for patients with lower extremity motor score (LEMS). Mean HRQOL changes at 6 weeks and 2 years compared with pre-op for patients with motor worsening were: ODI (+12.4 at 6 weeks and –4.7 at 2 years), SF-36v2 physical (–4.5 at 6 weeks and +2.3 at 2 years), SRS-22r (0.0 at 6 weeks and +0.4 at 2 years). Mean HRQOL changes for motor-neutral patients were: ODI (+0.6 at 6 weeks and –12.1 at 2 years), SF-36v2 physical (–1.6 at 6 weeks and +5.9 at 2 years), and SRS-22r (+0.4 at 6 weeks and +0.7 at 2 years). For patients with LEMS improvement, mean HRQOL changes were: ODI (–0.6 at 6 weeks and –16.3 at 2 years), SF-36v2 physical (+1.0 at 6 weeks and +7.0 at 2 years), and SRS-22r (+0.5 at 6 weeks and +0.9 at 2 years). Conclusion. In the subgroup of deformity patients who developed a new motor deficit, total HRQOLs and HRQOL changes were negatively impacted. Patients with more than 2 points of LEMS worsening had the worst changes, but still showed overall HRQOL improvement at 6 months and 2 years compared with pre-op baseline. Level of Evidence: 3 |
| وصف الملف: | application/pdf |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35e71a662edf34bb558b4aafe4cf234 https://curis.ku.dk/ws/files/321650390/Impact_of_New_Motor_Deficit_on_HRQOL_After_Adult.11.pdf |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....c35e71a662edf34bb558b4aafe4cf234 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |