Bacterial rhamnolipids and their 3-hydroxyalkanoate precursors activate Arabidopsis innate immunity through two independent mechanisms
| العنوان: | Bacterial rhamnolipids and their 3-hydroxyalkanoate precursors activate Arabidopsis innate immunity through two independent mechanisms |
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| المؤلفون: | Sandrine Dhondt-Cordelier, Jérôme Crouzet, Sandra Villaume, Stéphan Dorey, Sylvain Cordelier, Fabienne Baillieul, Corinna Dawid, Jean-Hugues Renault, Stefanie Ranf, Cyril Zipfel, Christophe Clément, Eric Déziel, Maude Cloutier, Alexander Kutschera, Charles Gauthier, Arvin Nickzad, Tim Gerster, Jane Hubert, Arnaud Haudrechy, Lin-Jie Shu, Marc Ongena, Florence Mazeyrat-Gourbeyre, Romain Schellenberger, Christian Schmid, Nicolas Borie, Thomas Hofmann |
| المساهمون: | Institut de Chimie Moléculaire de Reims - UMR 7312 (ICMR), SFR Condorcet, Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Centre National de la Recherche Scientifique (CNRS)-Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Centre National de la Recherche Scientifique (CNRS)-SFR CAP Santé (Champagne-Ardenne Picardie Santé), Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Université de Reims Champagne-Ardenne (URCA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), NatExplore, University of Zurich |
| المصدر: | Proceedings of the National Academy of Sciences of the United States of America Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (39), pp.e2101366118. ⟨10.1073/pnas.2101366118⟩ |
| بيانات النشر: | HAL CCSD, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | 0106 biological sciences, 0303 health sciences, Innate immune system, Multidisciplinary, biology, Chemistry, Pseudomonas, Plant Immunity, 580 Plants (Botany), biology.organism_classification, 01 natural sciences, Microbiology, 03 medical and health sciences, Immune system, 10126 Department of Plant and Microbial Biology, Immunity, Arabidopsis, mental disorders, Plant defense against herbivory, Arabidopsis thaliana, [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, [CHIM]Chemical Sciences, 10211 Zurich-Basel Plant Science Center, 030304 developmental biology, 010606 plant biology & botany |
| الوصف: | International audience; Plant innate immunity is activated upon perception of invasion pattern molecules by plant cell-surface immune receptors. Several bacteria of the genera Pseudomonas and Burkholderia produce rhamnolipids (RLs) from l -rhamnose and ( R )-3-hydroxyalkanoate precursors (HAAs). RL and HAA secretion is required to modulate bacterial surface motility, biofilm development, and thus successful colonization of hosts. Here, we show that the lipidic secretome from the opportunistic pathogen Pseudomonas aeruginosa , mainly comprising RLs and HAAs, stimulates Arabidopsis immunity. We demonstrate that HAAs are sensed by the bulb-type lectin receptor kinase LIPOOLIGOSACCHARIDE-SPECIFIC REDUCED ELICITATION/S-DOMAIN-1-29 (LORE/SD1-29), which also mediates medium-chain 3-hydroxy fatty acid (mc-3-OH-FA) perception, in the plant Arabidopsis thaliana . HAA sensing induces canonical immune signaling and local resistance to plant pathogenic Pseudomonas infection. By contrast, RLs trigger an atypical immune response and resistance to Pseudomonas infection independent of LORE. Thus, the glycosyl moieties of RLs, although abolishing sensing by LORE, do not impair their ability to trigger plant defense. Moreover, our results show that the immune response triggered by RLs is affected by the sphingolipid composition of the plasma membrane. In conclusion, RLs and their precursors released by bacteria can both be perceived by plants but through distinct mechanisms. |
| وصف الملف: | 525337_2_merged_1629220202.pdf - application/pdf; application/pdf |
| اللغة: | English |
| تدمد: | 0027-8424 1091-6490 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c391f9196291da7b3d3c3534ddf7eae3 https://hal.archives-ouvertes.fr/hal-03356415/document |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....c391f9196291da7b3d3c3534ddf7eae3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 00278424 10916490 |
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