Easy Access to Phosphine-Borane Building Blocks
| العنوان: | Easy Access to Phosphine-Borane Building Blocks |
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| المؤلفون: | Koop Lammertsma, J. Chris Slootweg, Martin Lutz, G. Bas de Jong, Nuria Ortega |
| المساهمون: | Synthetic Organic Chemistry (HIMS, FNWI), Chemistry and Pharmaceutical Sciences, AIMMS |
| المصدر: | Chemistry-A European Journal, 26(68), 15944-15952. Wiley-VCH Verlag de Jong, G B, Ortega, N, Lutz, M, Lammertsma, K & Slootweg, J C 2020, ' Easy Access to Phosphine-Borane Building Blocks ', Chemistry-A European Journal, vol. 26, no. 68, pp. 15944-15952 . https://doi.org/10.1002/chem.202002367 Chemistry (Weinheim an Der Bergstrasse, Germany) Chemistry-A European Journal, 26(68), 15944. Wiley |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 2019-20 coronavirus outbreak, synthesis, primary phosphine, Solid-state, Borane, 010402 general chemistry, 01 natural sciences, Catalysis, Inorganic Chemistry, chemistry.chemical_compound, crystal structures, Deprotonation, Moiety, phosphanediide, Protecting group, Alkyl, chemistry.chemical_classification, Full Paper, 010405 organic chemistry, Organic Chemistry, General Chemistry, Full Papers, Combinatorial chemistry, 0104 chemical sciences, chemistry, phosphine borane, SDG 6 - Clean Water and Sanitation, Phosphine |
| الوصف: | In this paper, we highlight the synthesis of a variety of primary phosphine‐boranes (RPH2⋅BH3) from the corresponding dichlorophosphines, simply by using Li[BH4] as reductant and provider of the BH3 protecting group. The method offers facile access not only to alkyl‐ and arylphosphine‐boranes, but also to aminophosphine‐boranes (R2NPH2⋅BH3) that are convenient building blocks but without the protecting BH3 moiety thermally labile and notoriously difficult to handle. The borane‐protected primary phosphines can be doubly deprotonated using n‐butyllithium to provide soluble phosphanediides Li2[RP⋅BH3] of which the phenyl‐derivative Li2[PhP⋅BH3] was structurally characterized in the solid state. A range of differently substituted primary phosphine‐boranes (RPH2⋅BH3) are now accessible that as unprotected phosphines difficult to handle or even unstable. In particular, the synthesis of the aminophosphane‐boranes (R2NPH2⋅BH3) offers new opportunities to use as versatile building blocks in the syntheses of organophosphorus compounds. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0947-6539 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e2851a54248243cfb7eabb572fbcd2 https://dare.uva.nl/personal/pure/en/publications/easy-access-to-phosphineborane-building-blocks(9c716722-21e1-4605-8ff2-5858654d6741).html |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....c3e2851a54248243cfb7eabb572fbcd2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 09476539 |
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