Left lateral segment pediatric liver transplantation: a 25 year experience at Mount Sinai

التفاصيل البيبلوغرافية
العنوان: Left lateral segment pediatric liver transplantation: a 25 year experience at Mount Sinai
المؤلفون: Marcelo Facciuto, Kishore Iyer, Parissa Tabrizian, Jaime Chu, Ronen Arnon, Sukru Emre, Matthew Holzner, Deniz Balci, Jang Moon, Yun Kyung Jung, Dylan Adamson, Sander Florman, Myron Schwartz
المصدر: HPB. 24:817-824
بيانات النشر: Elsevier BV, 2022.
سنة النشر: 2022
مصطلحات موضوعية: medicine.medical_specialty, Hepatology, business.industry, Liver Diseases, medicine.medical_treatment, Graft Survival, Metabolic disorder, Gastroenterology, Vascular complication, Liver transplantation, medicine.disease, Living donor, Liver Transplantation, Surgery, Liver disease, Hepatic artery thrombosis, Treatment Outcome, Living Donors, medicine, Humans, Lateral segment, Child, business, Fulminant liver failure, Retrospective Studies
الوصف: BACKGROUND Outcomes of left lateral segment (LLS) grafts in pediatric recipients were compared between living (LD-LLS) and deceased donor (DD-LLS) grafts. METHODS 195 LLS grafts (99DD-LLS-96LD-LLS) were analyzed with a median follow-up of 9.1years. The primary endpoints were overall patient/graft survival. RESULTS LD-LLS grafts were younger (0.9vs.1.4years, p = 0.039), more likely to have a fulminant liver failure (17.9%vs.5.3%,p = 0.002), less likely to have a metabolic disorder (6.3%vs.25.5%,p = 0.002), and less likely to be undergoing retransplantation (5.3% vs.16.2%,p = 0.015). There was a trend toward decreased hepatic artery thrombosis in LD-LLS grafts (6.6% vs. 15.5%,p = 0.054). No differences in the overall biliary complications occurred. The LD-LLS group had prolonged survival compared to the DD-LLS group with 10-year survival rates of 81%, and 74% (p = 0.005), respectively. LD-LLS grafts had longer graft survival compared to DD-LLS grafts (10-year graft survival 85%vs.67%,p = 0.005). Recipient age >1year (HR 2.39,p = 0.026), aortic reconstruction (HR 2.12,p = 0.046) and vascular complication (HR 3.12,p
تدمد: 1365-182X
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c475797bbe6217e0925ef2228c683634
https://doi.org/10.1016/j.hpb.2021.09.024
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....c475797bbe6217e0925ef2228c683634
قاعدة البيانات: OpenAIRE