التفاصيل البيبلوغرافية
| العنوان: |
Impact of cell division on intracellular uptake and nuclear targeting with fluorescent SiC-based nanoparticles |
| المؤلفون: |
Barbara Mognetti, Tetiana Serdiuk, Vladimir Lysenko, V. A. Skryshevsky, Alain Géloën |
| المصدر: |
Journal of Biophotonics. 6:291-297 |
| بيانات النشر: |
Wiley, 2012. |
| سنة النشر: |
2012 |
| مصطلحات موضوعية: |
inorganic chemicals, Cell division, Carbon Compounds, Inorganic, education, Cell, General Physics and Astronomy, Nanoparticle, Nanotechnology, General Biochemistry, Genetics and Molecular Biology, Mice, cell proliferation, nanoparticles, silicon carbide, fluorescence, 3T3-L1 Cells, medicine, Animals, General Materials Science, health care economics and organizations, Fluorescent Dyes, Cell Nucleus, Chemistry, Cell growth, Silicon Compounds, technology, industry, and agriculture, General Engineering, Contact inhibition, Biological Transport, General Chemistry, respiratory system, Fluorescence, Cell nucleus, medicine.anatomical_structure, Semiconductors, Biophysics, Cell Division, Intracellular |
| الوصف: |
Semiconductor nanoparticles (NPs) became important and wide-used tool for cell imaging because of their unique remarkable properties. Nevertheless, all previous investigations in this area were done on proliferating cells. For the first time, this work demonstrates strong influence of cell active proliferation/contact inhibition of proliferation on uptake of NPs. In addition, we show that cell division plays key-role in penetration of silicon carbide based NPs (SiC NPs) inside the cell nucleus. This may very likely concern other types of NPs able to reach the cell nuclei. In particular, observed effect of cell division gives perspectives for future selective cancer treatment with NPs. (© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) |
| تدمد: |
1864-063X |
| URL الوصول: |
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e1f9b906f33d8f45c11041e5cd5771
https://doi.org/10.1002/jbio.201200066 |
| حقوق: |
CLOSED |
| رقم الأكسشن: |
edsair.doi.dedup.....c4e1f9b906f33d8f45c11041e5cd5771 |
| قاعدة البيانات: |
OpenAIRE |
