Immunological profile changes following perioperative autologous vs. homologous blood transfusion in oncologic patients
| العنوان: | Immunological profile changes following perioperative autologous vs. homologous blood transfusion in oncologic patients |
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| المؤلفون: | Jan Oland, Suzana Kaufman, Yeheskel Levy, Rivka Yona, Shoshana Peller, Ruben Orda, Joel Sayfan |
| المصدر: | Journal of Surgical Oncology. 56:98-101 |
| بيانات النشر: | Wiley, 1994. |
| سنة النشر: | 1994 |
| مصطلحات موضوعية: | Adult, Male, Cellular immunity, medicine.medical_specialty, Blood transfusion, medicine.medical_treatment, Breast Neoplasms, Preoperative care, Gastroenterology, Blood Transfusion, Autologous, Immune system, Breast cancer, Internal medicine, Preoperative Care, Homologous chromosome, medicine, Humans, Blood Transfusion, Aged, Aged, 80 and over, Postoperative Care, Immunity, Cellular, business.industry, General Medicine, Perioperative, Middle Aged, medicine.disease, Oncology, Immunology, Female, Surgery, Colorectal Neoplasms, Erythrocyte Transfusion, business, Autotransfusion |
| الوصف: | To determine the effect of perioperative blood transfusion on immunological parameters, T cells, T-cell subsets, and concanavalin A-induced suppression were measured in 25 patients with colorectal and breast cancer. During the operation, 15 patients received autologous blood and 10 patients had homologous transfusion. The immunological status was again determined after curative surgery. Before surgery, normal percentage of T lymphocytes, decreased ratios of helper/suppressor cells, and impaired con A-induced suppression were found. Following the operation, the helper and suppressor cell percentages reversed to normal, whereas the con A-induced suppression remained impaired. This change was significantly more pronounced in patients who received autologous blood transfusion than in the other group. Autotransfusion has an impact on immune parameters that might prove less detrimental to the clinical outcome in oncologic surgery than homologous transfusion. |
| تدمد: | 1096-9098 0022-4790 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6275f09f8a0a9674e40e4c2daf76abb https://doi.org/10.1002/jso.2930560210 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....c6275f09f8a0a9674e40e4c2daf76abb |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10969098 00224790 |
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