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Quantification of left ventricular ejection fraction using through-time radial GRAPPA for real-time imaging

التفاصيل البيبلوغرافية
العنوان: Quantification of left ventricular ejection fraction using through-time radial GRAPPA for real-time imaging
المؤلفون: Vikas Gulani, Nicole Seiberlich, Vidya Nadig, Robert C. Gilkeson, Victoria Yeh
المصدر: Journal of Cardiovascular Magnetic Resonance, Vol 15, Iss Suppl 1, p P45 (2013)
Journal of Cardiovascular Magnetic Resonance
بيانات النشر: BMC, 2013.
سنة النشر: 2013
مصطلحات موضوعية: Medicine(all), Scanner, medicine.medical_specialty, lcsh:Diseases of the circulatory (Cardiovascular) system, Ejection fraction, Radiological and Ultrasound Technology, business.industry, Orientation (computer vision), Gating, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Ventricle, lcsh:RC666-701, Temporal resolution, Poster Presentation, medicine, Calibration, Radiology, Nuclear Medicine and imaging, Cardiology and Cardiovascular Medicine, business, Nuclear medicine, 030217 neurology & neurosurgery, Angiology
الوصف: Background Cardiac MRI requires a steady cardiac rhythm for ECGgating, and multiple breath-holds to minimize respiratory artifacts. By employing a non-Cartesian parallel imaging in form of through-time radial GRAPPA [1], accelerated imaging can be performed with temporal resolutions of < 50 ms, obviating the need for gating or breath-holding. breath-holding. We tested the hypothesis that volumetric measurements in the LV obtained with the real-time method could replace traditional measurements. Methods A total of 31 subjects (23 patients, 8 volunteers) were scanned on a 1.5T Avanto or 1.5T Espree scanner (Siemens Medical Solutions, Erlangen, Germany) using a combined spine and abdominal receiver array with 12 to 15 channels. The gold-standard cardiac functional examination was performed in a short-axis orientation with ECG gating, requiring 12-16 breathholds with the following parameters: Cartesian bSSFP sequence, TR~3162 ms, in plane resolution = 1.4-2.6 mm 2 , slice thickness = 6-8 mm, cardiac phases = 18-30. The real-time scans (26 calibration frames per slice and accelerated acquisition) were performed immediately following the goldstandard scan with no ECG gating or breath-holding: radial bSSFP sequence, TR= 2.64 ms, resolution = 2.3 mm 2 , slice thickness = 6-8 mm. A data acceleration factor of R=8 (16 projections for 128 x 128 matrix) was used such that the temporal resolution for real-time imaging was 42.2 ms per image. Calibration data for non-Cartesian GRAPPA reconstruction was acquired without ECG gating or breath-holds. After data collection and reconstruction, the blood volume in the left ventricle was assessed to determine the ESV, EDV, and EF for both methods. Results Bland-Altman analysis [2] was used to analyze the agreement between the two methods. This showed that 30 of the 31 of the EF measurements using traditional breath-hold imaging and the real-time free breathing method were within the 95% limits of agreement. The mean difference in LVEF between the two methods was -2% (breath-hold minus real-time). All 31 measurements of EDV using both methods were within 95% limits of agreement. The mean difference in EDV between the two methods was -4ml. 30/ 31 measurements of ESV using both methods were within the 95% limits of agreement. The mean difference in ESV between the two methods was 2 ml. The differences in EF, EDV, and ESV are not clinically significant [3]. Conclusions Our results show no significant statistical or clinical difference between volumetric analysis determined using standard breathhold cine imaging and through-time radial GRAPPA. This indicates that standard method can be replaced by the real-time imaging approach which can be used even for patients with arrhythmia or difficulty with breath-holding. Funding
اللغة: English
تدمد: 1097-6647
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69b6dedbb3e79c1b590020acf56370e
https://doaj.org/article/bb4b1889ec394348a37f719f4e34c1bc
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....c69b6dedbb3e79c1b590020acf56370e
قاعدة البيانات: OpenAIRE
الوصف
تدمد:10976647