[Pathogenic mechanisms of SARS-CoV-2 infection and kidney disease: a clinical and molecular perspective]
| العنوان: | [Pathogenic mechanisms of SARS-CoV-2 infection and kidney disease: a clinical and molecular perspective] |
|---|---|
| المؤلفون: | M J Puchades, O Medina, Luis D'Marco, V Lameda, Wheeler Torres, Valmore Bermúdez, X. E. Guerra-Torres, H Parra, A Manzano, Manuel Nava, M K Suarez, Valery Morillo |
| المصدر: | Anales del Sistema Sanitario De Navarra r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA instname |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, business.industry, SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Public health, Acute kidney injury, Renal function, COVID-19, General Medicine, Acute respiratory distress, Acute Kidney Injury, medicine.disease, Virus, Immune system, Immunology, Medicine, Humans, Renal Insufficiency, Chronic, business, Kidney disease |
| الوصف: | The SARS-CoV-2 infection has become as a worldwide public health emergency. It exhibits a variety of clinical presentations, ranging from benign to acute respiratory distress syndrome, systemic involvement, and multiorganic failure. The severity of the clinical picture depends on host and virus biological features and the presence of comorbidities such as chronic kidney disease. In addition, the interaction between the virus, angiotensin-converting enzyme 2, and the exacerbated immune response could lead to the development of acute kidney injury. However, the implications of SARS-CoV-2 infection on renal cells, the prognosis of patients with chronic kidney disease, and the long-term behavior of renal function are not entirely understood. This review aims to explore the role of SARS-CoV-2 in acute and chronic kidney disease and the possible pathogenic mechanisms of renal involvement. |
| تدمد: | 2340-3527 1137-6627 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6bd0d09ee7e6ce23f98d9c1ba80c326 https://pubmed.ncbi.nlm.nih.gov/34664556 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....c6bd0d09ee7e6ce23f98d9c1ba80c326 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23403527 11376627 |
|---|