Cytotoxic cobalt (III) Schiff base complexes: in vitro anti-proliferative, oxidative stress and gene expression studies in human breast and lung cancer cells
| العنوان: | Cytotoxic cobalt (III) Schiff base complexes: in vitro anti-proliferative, oxidative stress and gene expression studies in human breast and lung cancer cells |
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| المؤلفون: | Balakrishnan Gowdhami, Yesaiyan Manojkumar, R. T. V. Vimala, Venkatesan Ramya, Balakrishnan Karthiyayini, Balamuthu Kadalmani, Mohammad Abdulkader Akbarsha |
| المصدر: | BioMetals. 35:67-85 |
| بيانات النشر: | Springer Science and Business Media LLC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Biomaterials, Oxidative Stress, Lung Neoplasms, Coordination Complexes, Metals and Alloys, Gene Expression, Humans, Antineoplastic Agents, Apoptosis, Cobalt, General Agricultural and Biological Sciences, Schiff Bases, General Biochemistry, Genetics and Molecular Biology |
| الوصف: | Increasing cancer drug chemo-resistance, especially in the treatment of breast and lung cancers, alarms the immediate need of newer and effective anticancer drugs. Until now, chemotherapeutics based on metal complexes are considered the most effective treatment modality. In the present study, we have evaluated the cytotoxic effect of two cobalt (III) Schiff base complexes based on the leads from complex combinatorial chemistry. Cobalt (III) Schiff base complexes (Complex 3 = Co(Ph-acacen)(HA) |
| تدمد: | 1572-8773 0966-0844 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70fc8c3d698c49f2d8220e644a93045 https://doi.org/10.1007/s10534-021-00351-8 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....c70fc8c3d698c49f2d8220e644a93045 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 15728773 09660844 |
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