Peripheral blood stem cells collected before and after leukapheresis in the very early remission phase of hematopoietic malignancies
| العنوان: | Peripheral blood stem cells collected before and after leukapheresis in the very early remission phase of hematopoietic malignancies |
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| المؤلفون: | Dominique Bastit, E. Sumereau-Dassin, J. P. Vannier, Hervé Tilly, Mathieu Monconduit, P. Jean, H. Piguet |
| المصدر: | European Journal of Haematology. 42:481-486 |
| بيانات النشر: | Wiley, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | Adult, Time Factors, Lymphoma, medicine.medical_treatment, Hematopoietic stem cell transplantation, Transplantation, Autologous, Humans, Medicine, Leukapheresis, Progenitor cell, Chemotherapy, business.industry, Graft Survival, Remission Induction, Hematopoietic Stem Cell Transplantation, Hematology, General Medicine, Precursor Cell Lymphoblastic Leukemia-Lymphoma, medicine.disease, Hodgkin Disease, Leukemia, Myeloid, Acute, Leukemia, Haematopoiesis, Immunology, Stem cell, business, Megakaryocytes |
| الوصف: | Human peripheral blood obtained after chemotherapy-induced remission in hemopoietic malignancies has been suggested to be a potential substitute for autologous bone marrow as regards autologous hematopoietic reconstitution. The schedule and consequences of early leukapheresis are, however, still imprecise. We report a study performed in two series of, respectively, 10 and 14 patients where sequential leukapheresis (total number = 84) was evaluated with regard to colony-forming unit (CFU) potency. Our data demonstrate that adequate numbers of progenitor cells can be collected by leukapheresis and that, even when this is performed at an early stage after remission, subsequent hematopoietic reconstitution is not impaired. |
| تدمد: | 1600-0609 0902-4441 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7dfd732f2313fd4618e57e026eca47b https://doi.org/10.1111/j.1600-0609.1989.tb01474.x |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....c7dfd732f2313fd4618e57e026eca47b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16000609 09024441 |
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