Can X-Ray Powder Diffraction Be a Suitable Forensic Method for Illicit Drug Identification?
| العنوان: | Can X-Ray Powder Diffraction Be a Suitable Forensic Method for Illicit Drug Identification? |
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| المؤلفون: | Bronislav Jurásek, František Králík, Vilém Bartůněk, Vladimír Setnička, Martin Kuchař, Daniel Svozil, Štěpán Huber, Wim Dehaen, Patrik Fagan |
| المصدر: | Frontiers in Chemistry, Vol 8 (2020) Frontiers in Chemistry |
| بيانات النشر: | Frontiers Media S.A., 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Materials science, Sample (material), Infrared spectroscopy, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Drug detection, lcsh:Chemistry, symbols.namesake, Mephedrone, drug detection, medicine, Butylone, infrared spectroscopy, Original Research, Chromatography, General Chemistry, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Chemistry, lcsh:QD1-999, Naphyrone, new psychoactive substances, X-ray powder diffraction, Raman spectroscopy, symbols, 0210 nano-technology, Powder diffraction, medicine.drug |
| الوصف: | New psychoactive substances (NPSs) are associated with a significant number of intoxications. With the number of readily available forms of these drugs rising every year, there are even risks for the general public. Consequently, there is a high demand for methods sufficiently sensitive to detect NPSs in samples found at the crime scene. Infrared (IR) and Raman spectroscopies are commonly used for such detection, but they have limitations; for example, fluorescence in Raman can overlay the signal and when the sample is a mixture sometimes neither Raman nor IR is able to identify the compounds. Here, we investigate the potential of X-ray powder diffraction (XRPD) to analyse samples seized on the black market. A series of psychoactive substances (heroin, cocaine, mephedrone, ephylone, butylone, JWH-073, and naphyrone) was measured. Comparison of their diffraction patterns with those of the respective standards showed that XRPD was able to identify each of the substances. The same samples were analyzed using IR and Raman, which in both cases were not able to detect the compounds in all of the samples. These results suggest that XRPD could be a valuable addition to the range of forensic tools used to detect these compounds in illicit drug samples. |
| اللغة: | English |
| تدمد: | 2296-2646 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a4c27a2b441c68d23319627d26ef5f https://www.frontiersin.org/article/10.3389/fchem.2020.00499/full |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....c8a4c27a2b441c68d23319627d26ef5f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22962646 |
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