GP consultation rates for sequelae after acute covid-19 in patients managed in the community or hospital in the UK: population based study

التفاصيل البيبلوغرافية
العنوان: GP consultation rates for sequelae after acute covid-19 in patients managed in the community or hospital in the UK: population based study
المؤلفون: Hannah R Whittaker, Claudia Gulea, Ardita Koteci, Constantinos Kallis, Ann D Morgan, Chukwuma Iwundu, Mark Weeks, Rikisha Gupta, Jennifer K Quint
المصدر: BMJ (Clinical research ed.). 375
سنة النشر: 2021
مصطلحات موضوعية: Male, Office Visits, SARS-CoV-2, COVID-19, General Medicine, Venous Thromboembolism, Middle Aged, State Medicine, United Kingdom, Hospitalization, General Practitioners, Humans, Female, Community Health Services, Pandemics, Proportional Hazards Models
الوصف: ObjectivesTo describe the rates for consulting a general practitioner (GP) for sequelae after acute covid-19 in patients admitted to hospital with covid-19 and those managed in the community, and to determine how the rates change over time for patients in the community and after vaccination for covid-19.DesignPopulation based study.Setting1392 general practices in England contributing to the Clinical Practice Research Datalink Aurum database.Participants456 002 patients with a diagnosis of covid-19 between 1 August 2020 and 14 February 2021 (44.7% men; median age 61 years), admitted to hospital within two weeks of diagnosis or managed in the community, and followed-up for a maximum of 9.2 months. A negative control group included individuals without covid-19 (n=38 511) and patients with influenza before the pandemic (n=21 803).Main outcome measuresComparison of rates for consulting a GP for new symptoms, diseases, prescriptions, and healthcare use in individuals admitted to hospital and those managed in the community, separately, before and after covid-19 infection, using Cox regression and negative binomial regression for healthcare use. The analysis was repeated for the negative control and influenza cohorts. In individuals in the community, outcomes were also described over time after a diagnosis of covid-19, and compared before and after vaccination for individuals who were symptomatic after covid-19 infection, using negative binomial regression.ResultsRelative to the negative control and influenza cohorts, patients in the community (n=437 943) had significantly higher GP consultation rates for multiple sequelae, and the most common were loss of smell or taste, or both (adjusted hazard ratio 5.28, 95% confidence interval 3.89 to 7.17, PConclusionsGP consultation rates for sequelae after acute covid-19 infection differed between patients with covid-19 who were admitted to hospital and those managed in the community. For individuals in the community, rates of some sequelae decreased over time but those for others, such as anxiety and depression, persisted. Rates of some outcomes decreased after vaccination in this group.
تدمد: 1756-1833
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c900f50fc3d4b0f3585b19e605640f74
https://pubmed.ncbi.nlm.nih.gov/34965928
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....c900f50fc3d4b0f3585b19e605640f74
قاعدة البيانات: OpenAIRE