Applicability of ISNT and IST rules to the retinal nerve fibre layer using spectral domain optical coherence tomography in early glaucoma
| العنوان: | Applicability of ISNT and IST rules to the retinal nerve fibre layer using spectral domain optical coherence tomography in early glaucoma |
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| المؤلفون: | Paaraj Dave, Juhi Shah |
| المصدر: | British Journal of Ophthalmology. 99:1713-1717 |
| بيانات النشر: | BMJ, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Male, Retinal Ganglion Cells, medicine.medical_specialty, Refractive error, Intraocular pressure, Visual acuity, genetic structures, Optic Disk, Visual Acuity, Optic disk, Glaucoma, Sensitivity and Specificity, Ophthalmoscopy, Cellular and Molecular Neuroscience, Nerve Fibers, Optical coherence tomography, Ophthalmology, Optic Nerve Diseases, medicine, Humans, Prospective Studies, Intraocular Pressure, Aged, Likelihood Functions, medicine.diagnostic_test, business.industry, Middle Aged, medicine.disease, eye diseases, Sensory Systems, Cross-Sectional Studies, Optic nerve, Female, sense organs, Visual Fields, medicine.symptom, business, Tomography, Optical Coherence |
| الوصف: | To report the applicability of ISNT (inferiorsuperiornasaltemporal) and IST (inferiorsuperiortemporal) rules on the retinal nerve fibre layer (RNFL) using spectral domain optical coherence tomography (SD-OCT) for detecting early glaucoma.A prospective, cross-sectional study which included 80 eyes of 80 normal subjects and 76 eyes of 76 patients with early glaucoma by Hodapp-Anderson-Parrish classification. All subjects were of age more than 18 years, best corrected visual acuity 20/40 or better and a refractive error within ±5 dioptres (D) sphere and ±3 D cylinder. Control subjects had a normal ocular examination, intraocular pressure22 mm Hg, no past history of high intraocular pressure, no family history of glaucoma, normal optic disc morphology and visual field. All eyes underwent SD-OCT examination for RNFL analysis. The sensitivity, specificity and likelihood ratio for violation of ISNT and IST rules was calculated for early glaucoma diagnosis.The ISNT rule was followed by 44 (55%) normal and 28 (36.84%) early glaucoma eyes. The IST rule was followed by 48 (60%) normal and 40 (52.63%) early glaucoma eyes. The sensitivity/specificity for violation of ISNT and IST rules for early glaucoma diagnosis was 63.2%/55% and 47.4%/60% respectively. The positive/negative likelihood ratio for ISNT and IST rules was 1.4/0.67 and 1.2/0.88, respectively, for diagnosing early glaucoma.Even though useful during ophthalmoscopy, ISNT and IST rules by themselves don't clearly distinguish normal eyes from those with glaucoma when applied to the quadrant values on RNFL on SD-OCT examination. |
| تدمد: | 1468-2079 0007-1161 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c919f5f77d0d5ae73a8f71ae80c6bf52 https://doi.org/10.1136/bjophthalmol-2014-306331 |
| رقم الأكسشن: | edsair.doi.dedup.....c919f5f77d0d5ae73a8f71ae80c6bf52 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14682079 00071161 |
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