Essential Fructosuria: Increased Levels of Fructose 3-Phosphate in Erythrocytes
| العنوان: | Essential Fructosuria: Increased Levels of Fructose 3-Phosphate in Erythrocytes |
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| المؤلفون: | A Petersen, B Steinmann, R Gitzelmann |
| المصدر: | Enzyme. 46:319-323 |
| بيانات النشر: | S. Karger AG, 1992. |
| سنة النشر: | 1992 |
| مصطلحات موضوعية: | Adult, medicine.medical_specialty, Erythrocytes, Fructose, Carbohydrate metabolism, Biochemistry, chemistry.chemical_compound, Essential fructosuria, Reference Values, Internal medicine, Diabetes mellitus, medicine, Humans, Glycated Hemoglobin, Fructosephosphates, medicine.disease, Red blood cell, Endocrinology, medicine.anatomical_structure, chemistry, Fructolysis, Sorbitol, Biomarkers, Carbohydrate Metabolism, Inborn Errors |
| الوصف: | Erythrocytes of 3 adult siblings with essential fructosuria contained 45-200 mumol/l fructose 3-phosphate (Fru-3-P), i.e. 3-15 times the concentration in normal controls. Sorbitol 3-phosphate was also increased, but to a lesser degree. An oral load with 50 g of fructose produced an additional 40 mumol/l increase of erythrocyte Fru-3-P after 5 h. The rate of Fru-3-P formation by red cells in vitro was normal. HbA1 and HbA1c were normal. The suspected pathogenetic role of Fru-3-P in diabetic complications is questioned. |
| تدمد: | 2504-2564 0013-9432 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9bf4e97b6945edffdfdd3d40812d867 https://doi.org/10.1159/000468811 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....c9bf4e97b6945edffdfdd3d40812d867 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 25042564 00139432 |
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