18F-fluorodeoxyglucose and11C-acetate positron emission tomography are useful modalities for diagnosing the histologic type of thymoma
| العنوان: | 18F-fluorodeoxyglucose and11C-acetate positron emission tomography are useful modalities for diagnosing the histologic type of thymoma |
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| المؤلفون: | Tomoyuki Goya, Rumi Nakashima, Ken-ichi Iyama, Kimiichi Uno, Katsumi Tomiyoshi, Kazuya Sakaguchi, Masahiro Kaji, Hiroaki Nomori, Takashi Suzuki, Hirotoshi Horio, Hidekatsu Shibata |
| المصدر: | Cancer. 115:2531-2538 |
| بيانات النشر: | Wiley, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | Adult, Male, Cancer Research, Pathology, medicine.medical_specialty, Thymoma, Standardized uptake value, 11c acetate, Fluorodeoxyglucose F18, hemic and lymphatic diseases, medicine, Histologic type, Humans, Neoplasm Invasiveness, Carbon Radioisotopes, Stage (cooking), neoplasms, Aged, Fluorodeoxyglucose, medicine.diagnostic_test, business.industry, Cancer, Thymus Neoplasms, Middle Aged, medicine.disease, Oncology, Positron emission tomography, Positron-Emission Tomography, Female, business, medicine.drug |
| الوصف: | BACKGROUND: The objective of this study was to clarify the usefulness of positron emission tomography (PET) using18F-fluorodeoxyglucose (FDG) and carbon 11-labeled acetate (AC) for predicting the histologic types and tumor invasiveness of thymoma in a multicenter study. METHODS: Forty thymomas were examined using both FDG-PET and AC-PET before surgery. The histologic types were type A in 1 thymoma, type AB in 12 thymomas, type B1 in 11 thymomas, type B2 in 7 thymomas, type B3 in 6 thymomas, and type C in 3 thymomas. Tumor invasiveness was assessed by pathologic tumor stage and was identified as stage I in 17 tumors, stage II in 17 tumors, stage III in 4 tumors, and stage IV in 2 tumors. FDG and AC uptake was measured as the maximum standard uptake value (SUV). RESULTS: The FDG-SUV in type C thymomas was significantly higher than that in the other types (A-B3; P = .001 – P = .048). The AC-SUV in type A/AB thymomas was significantly higher than that in the other tumor types (B1-C; P < .001 – P = .002). All 3 type C tumors had an FDG-SUV ≥6.3, and all 13 type A/AB tumors had an FDG-SUV |
| تدمد: | 1097-0142 0008-543X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf8a8b06f5053c08cdd7a175f8cd4ea https://doi.org/10.1002/cncr.24278 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....caf8a8b06f5053c08cdd7a175f8cd4ea |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10970142 0008543X |
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