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Abdominal Aortic Aneurysms with High Thrombus Signal Intensity on Magnetic Resonance Imaging are Associated with High Growth Rate

التفاصيل البيبلوغرافية
العنوان: Abdominal Aortic Aneurysms with High Thrombus Signal Intensity on Magnetic Resonance Imaging are Associated with High Growth Rate
المؤلفون: Femke A. M. V. I. Hellenthal, G.W.H. Schurink, M.C.J. Wishaupt, VL Nguyen, Walter H. Backes, Sylvia Heeneman, ME Marianne Eline Kooi, Tim Leiner, R.J. van der Geest
المساهمون: RS: NUTRIM - R1 - Metabolic Syndrome, RS: CARIM - R3 - Vascular biology, RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, RS: GROW - Oncology, RS: GROW - R2 - Basic and Translational Cancer Biology, Beeldvorming, Surgery, Pathologie
المصدر: European Journal of Vascular and Endovascular Surgery, 48(6), 676-684
European Journal of Vascular and Endovascular Surgery, 48(6), 676-684. Elsevier Saunders
بيانات النشر: Elsevier Saunders, 2014.
سنة النشر: 2014
مصطلحات موضوعية: Male, Time Factors, HIGH-ATTENUATING CRESCENT, GUIDELINES, RUPTURE, Aorta, Abdominal, Prospective Studies, Growth rate, MR-ANGIOGRAPHY, Medicine(all), Aged, 80 and over, medicine.diagnostic_test, Middle Aged, Abdominal aortic aneurysm, Disease Progression, cardiovascular system, Female, Radiology, Cardiology and Cardiovascular Medicine, Thrombus, Dilatation, Pathologic, medicine.medical_specialty, Coefficient of variation, SOCIETY, VASCULAR-SURGERY, INTRALUMINAL THROMBUS, WALL STRESS, Aneurysm, Magnetic resonance imaging, INFLAMMATION, Predictive Value of Tests, medicine, Humans, Intraluminal thrombus, cardiovascular diseases, Aged, business.industry, Aneurysm growth, DIAMETER, Reproducibility of Results, Thrombosis, medicine.disease, Surgery, Signal intensity, business, Aortic Aneurysm, Abdominal, Follow-Up Studies
الوصف: Objectives A layer of intraluminal thrombus is commonly observed in abdominal aortic aneurysms (AAAs). The purpose of this study was to investigate whether AAAs with high thrombus signal intensity (SI) at T1-weighted (T1w) magnetic resonance imaging (MRI) exhibit a faster aneurysm growth rate. Methods This was a prospective follow-up study. Patients with a small AAA underwent MRI examinations at 6 month intervals. Aneurysm thrombus and psoas muscle SI at the point of maximal diameter on T1w images were measured and expressed as a ratio (thrombus SI/muscle SI). Based on these measurements, patients were categorized into three groups: AAA with relative thrombus SI above (group A) and below (group B) the mean relative thrombus SI of 1.20. Patients with AAA without thrombus constituted group C. Eight patients were scanned twice within 2 weeks to investigate scan–rescan reproducibility. Aneurysm growth rates were expressed as the change in maximal cross sectional area (cm2). Results A total of 35 patients (m/f: 26/9; age 72 ± 7 years; AAA maximal diameter 4.9 ± 0.5 cm) were included. Mean aneurysm growth rate for patients in group A (n = 11, 1.87 cm2/0.5 year) was two-fold higher than group B (n = 17, 0.78 cm2/0.5 year, p = .005) and eight-fold higher than group C (n = 7, 0.23 cm2/0.5 years, p = .004) at 6 months' follow-up. At 12 months' follow-up, the mean aneurysm growth rate remained significantly higher in group A (n = 7, 3.03 cm2/year) than groups B (n = 10, 1.63 cm2/year, p = .03) and C (n = 7, 0.73 cm2/year, p = .004). The reproducibility for thrombus SI measurements was found to be high with a coefficient of variation of 6.2%. Aneurysm maximal cross-sectional area at baseline was not significantly different for the three groups. Conclusions Abdominal aortic aneurysms with high thrombus SI on T1w MR images are associated with higher aneurysm growth rates.
اللغة: English
تدمد: 1532-2165
1078-5884
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb18a8d9963540de2324e70f389e99cb
https://doi.org/10.1016/j.ejvs.2014.04.025
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....cb18a8d9963540de2324e70f389e99cb
قاعدة البيانات: OpenAIRE
الوصف
تدمد:15322165
10785884