Immediate renal Doppler ultrasonography findings (<24 h) and its association with graft survival

التفاصيل البيبلوغرافية
العنوان: Immediate renal Doppler ultrasonography findings (<24 h) and its association with graft survival
المؤلفون: Jorge Rioja, David Rosell, José Enrique Robles, Alberto Benito, Zudaire Jj, Javier Barba, Pedro Errasti, Berián Jm, A. Rincón, Ignacio Pascual
المصدر: World Journal of Urology. 29:547-553
بيانات النشر: Springer Science and Business Media LLC, 2011.
سنة النشر: 2011
مصطلحات موضوعية: Adult, Male, Nephrology, medicine.medical_specialty, Time Factors, Urology, Kaplan-Meier Estimate, Kidney, Predictive Value of Tests, Internal medicine, Humans, Medicine, Postoperative Period, Hydronephrosis, Kidney transplantation, Survival analysis, Proportional Hazards Models, Retrospective Studies, Univariate analysis, business.industry, Graft Survival, Ultrasonography, Doppler, Retrospective cohort study, Odds ratio, Middle Aged, medicine.disease, Kidney Transplantation, Surgery, Transplantation, Female, business, Follow-Up Studies
الوصف: Renal Doppler ultrasonography (DUS) is the gold-standard image test for follow-up after renal transplantation, it is potentially useful to detect renal disease and it could be related with long-term survival. We evaluate whether renal graft survival can be predicted by immediate renal Doppler ultrasonography (IRDUS), defined as ultrasonography carried out in the first 24 h post-surgery. Immediate renal DUS findings (resistance index, hydronephrosis, fluid collection, bruises, and vascularization abnormalities) and their association with graft survival were analyzed in a retrospective observational study of 343 renal allografts. Renal transplantation was done using a standard technique, and DUS was performed 24 h post-transplantation. The association of variables with graft survival was evaluated by Cox univariate and multivariate proportional hazards analysis. Kaplan–Meier survival analysis and the log-rank test were used to examine graft survival. The follow-up median was 85 months. On IRDUS, 137 patients (39.9%) had abnormal findings. The best RI cutpoint for the prediction of graft survival was 0.7; therefore, we defined two different groups: RI ≤ 0.7 (n = 247) versus RI > 0.7 (n = 96). Univariate analysis revealed that graft survival was significantly lower in patients with RI > 0.7 (P ≤ 0.001), vascularization abnormalities (P ≤ 0.001) or bruises (P = 0.026). In multivariate analysis, the only factors independently associated with graft survival were RI (odds ratio 2.4; 95% CI 1.4–4.1) and vascularization abnormalities (odds ratio 2.7; 95% CI 1.1–6.5). IRDUS can be useful, besides being highly useful in the diagnosis of graft primary dysfunction in the transplanted patient also yields information that can help to predict long-term graft survival.
تدمد: 1433-8726
0724-4983
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2eae94cd627c094656c71b9ecba9e8
https://doi.org/10.1007/s00345-011-0666-3
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....cb2eae94cd627c094656c71b9ecba9e8
قاعدة البيانات: OpenAIRE